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The cytotoxic potential of household waste during composting

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Bibliographic Details
Title:	The cytotoxic potential of household waste during composting
Authors:	Sigsgaard, T., Roepstorff, V.
Source:	Waste Management & Research: The Journal for a Sustainable Circular Economy. Apr1997, Vol. 15 Issue 2, p189. 0p.
Subjects:	Composting
Abstract:	During the last 10 years an increasing number of plants for re-use of refuse have been constructed in Europe and the U.S.A. During the same period several cases of occupational respiratory diseases among workers have been reported in the recycling industry. The aim of this project was to show, in vitro, if there is any change in the cytotoxicpotential of garbage dust during the process of converting householdwaste to compost. Two cell lines have been exposed to extracts of waste fuel pellets and compost, taken from three different time periodsin the composting process. Significant differences were found in thecytotoxic potential of extracts of household waste (P<0.05). Extracts of 0.48 mg well- 1 raw compost, fresh compost and matured compost show a cytotoxic effect at 97, 41 and 44%, respectively of unexposed cells. In conclusion, these results show the greatest cytotoxic potential when the microbial activity seems to be at its height in the composting process. Earlier, studies on the effect of endotoxin (lipopolysaccharide, LPS) on the cells, and with pure endotoxin didnot find any cytotoxic effect in the assay. Further investigations are needed in order to find which micro-organisms or components from these are responsible for the cytotoxic potential. [ABSTRACT FROM AUTHOR]
	Copyright of Waste Management & Research: The Journal for a Sustainable Circular Economy is the property of Sage Publications, Ltd. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database:	Engineering Source

Description
Abstract:	During the last 10 years an increasing number of plants for re-use of refuse have been constructed in Europe and the U.S.A. During the same period several cases of occupational respiratory diseases among workers have been reported in the recycling industry. The aim of this project was to show, in vitro, if there is any change in the cytotoxicpotential of garbage dust during the process of converting householdwaste to compost. Two cell lines have been exposed to extracts of waste fuel pellets and compost, taken from three different time periodsin the composting process. Significant differences were found in thecytotoxic potential of extracts of household waste (P<0.05). Extracts of 0.48 mg well- 1 raw compost, fresh compost and matured compost show a cytotoxic effect at 97, 41 and 44%, respectively of unexposed cells. In conclusion, these results show the greatest cytotoxic potential when the microbial activity seems to be at its height in the composting process. Earlier, studies on the effect of endotoxin (lipopolysaccharide, LPS) on the cells, and with pure endotoxin didnot find any cytotoxic effect in the assay. Further investigations are needed in order to find which micro-organisms or components from these are responsible for the cytotoxic potential. [ABSTRACT FROM AUTHOR]
ISSN:	0734242X