Ultrashort echo imaging of cyclically loaded rabbit patellar tendon.
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| Title: | Ultrashort echo imaging of cyclically loaded rabbit patellar tendon. |
|---|---|
| Authors: | Koff, Matthew F.1 koffm@hss.edu, Pownder, Sarah L.1, Shah, Parina H.1, Yang, Lim Wei1, Potter, Hollis G.1 |
| Source: | Journal of Biomechanics. 2014, Vol. 47 Issue 13, p3428-3432. 5p. |
| Subjects: | Patellar tendon, Rabbit physiology, Tendinitis, Joint diseases, Cyclic loads, Magnetic resonance imaging, Physiology |
| Abstract: | Tendinopathy affects individuals who perform repetitive joint motion. Magnetic resonance imaging (MRI) is frequently used to qualitatively assess tendon health, but quantitative evaluation of inherent MRI properties of loaded tendon has been limited. This study evaluated the effect of cyclic loading on T2* values of fresh and frozen rabbit patellar tendons using ultra short echo (UTE) MRI. Eight fresh and 8 frozen rabbit lower extremities hadMR scans acquired for tendon T2* evaluation. The tendons were then manually cyclically loaded for 100 cycles to 45 N at approximately 1 Hz. The MR scanning was repeated to reassess the T2* values. Analyses were performed to detect differences of tendon T2* values between fresh and frozen samples prior to and after loading, and to detect changes of tendon T2*values between the unloaded and loaded configurations. No difference of T2* was found between the fresh and frozen samples prior to or after loading, p = 0.8 and p = 0.1, respectively. The tendons had significantly shorter T2* values, p=0.023, and reduced T2* variability, p=0.04, after cyclicloading. Histologic evaluation confirmed no induced tendon damage from loading. Shorter T2*, from stronger spin-spin interactions, may be attributed to greater tissue organization from uncrimping of collagen fibrils and lateral contraction of the tendon during loading. Cyclic tensile loading of tissue reduces patellar tendon T2* values and may provide a quantitative metric to assess tissue organization. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Biomechanics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 98680838 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Ultrashort echo imaging of cyclically loaded rabbit patellar tendon. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Koff%2C+Matthew+F%2E%22">Koff, Matthew F.</searchLink><relatesTo>1</relatesTo><i> koffm@hss.edu</i><br /><searchLink fieldCode="AR" term="%22Pownder%2C+Sarah+L%2E%22">Pownder, Sarah L.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Shah%2C+Parina+H%2E%22">Shah, Parina H.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Yang%2C+Lim+Wei%22">Yang, Lim Wei</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Potter%2C+Hollis+G%2E%22">Potter, Hollis G.</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Biomechanics%22">Journal of Biomechanics</searchLink>. 2014, Vol. 47 Issue 13, p3428-3432. 5p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Patellar+tendon%22">Patellar tendon</searchLink><br /><searchLink fieldCode="DE" term="%22Rabbit+physiology%22">Rabbit physiology</searchLink><br /><searchLink fieldCode="DE" term="%22Tendinitis%22">Tendinitis</searchLink><br /><searchLink fieldCode="DE" term="%22Joint+diseases%22">Joint diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Cyclic+loads%22">Cyclic loads</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Physiology%22">Physiology</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Tendinopathy affects individuals who perform repetitive joint motion. Magnetic resonance imaging (MRI) is frequently used to qualitatively assess tendon health, but quantitative evaluation of inherent MRI properties of loaded tendon has been limited. This study evaluated the effect of cyclic loading on T2* values of fresh and frozen rabbit patellar tendons using ultra short echo (UTE) MRI. Eight fresh and 8 frozen rabbit lower extremities hadMR scans acquired for tendon T2* evaluation. The tendons were then manually cyclically loaded for 100 cycles to 45 N at approximately 1 Hz. The MR scanning was repeated to reassess the T2* values. Analyses were performed to detect differences of tendon T2* values between fresh and frozen samples prior to and after loading, and to detect changes of tendon T2*values between the unloaded and loaded configurations. No difference of T2* was found between the fresh and frozen samples prior to or after loading, p = 0.8 and p = 0.1, respectively. The tendons had significantly shorter T2* values, p=0.023, and reduced T2* variability, p=0.04, after cyclicloading. Histologic evaluation confirmed no induced tendon damage from loading. Shorter T2*, from stronger spin-spin interactions, may be attributed to greater tissue organization from uncrimping of collagen fibrils and lateral contraction of the tendon during loading. Cyclic tensile loading of tissue reduces patellar tendon T2* values and may provide a quantitative metric to assess tissue organization. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Biomechanics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jbiomech.2014.08.018 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 3428 Subjects: – SubjectFull: Patellar tendon Type: general – SubjectFull: Rabbit physiology Type: general – SubjectFull: Tendinitis Type: general – SubjectFull: Joint diseases Type: general – SubjectFull: Cyclic loads Type: general – SubjectFull: Magnetic resonance imaging Type: general – SubjectFull: Physiology Type: general Titles: – TitleFull: Ultrashort echo imaging of cyclically loaded rabbit patellar tendon. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Koff, Matthew F. – PersonEntity: Name: NameFull: Pownder, Sarah L. – PersonEntity: Name: NameFull: Shah, Parina H. – PersonEntity: Name: NameFull: Yang, Lim Wei – PersonEntity: Name: NameFull: Potter, Hollis G. IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 09 Text: 2014 Type: published Y: 2014 Identifiers: – Type: issn-print Value: 00219290 Numbering: – Type: volume Value: 47 – Type: issue Value: 13 Titles: – TitleFull: Journal of Biomechanics Type: main |
| ResultId | 1 |
