Measuring Repetitive Behaviors as a Treatment Endpoint in Youth with Autism Spectrum Disorder

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Bibliographic Details
Title: Measuring Repetitive Behaviors as a Treatment Endpoint in Youth with Autism Spectrum Disorder
Language: English
Authors: Scahill, Lawrence, Aman, Michael G., Lecavalier, Luc, Halladay, Alycia K., Bishop, Somer L., Bodfish, James W., Grondhuis, Sabrina, Jones, Nancy, Horrigan, Joseph P., Cook, Edwin H., Handen, Benjamin L., King, Bryan H., Pearson, Deborah A., McCracken, James T., Sullivan, Katherine Anne, Dawson, Geraldine
Source: Autism: The International Journal of Research and Practice. Jan 2015 19(1):38-52.
Availability: SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: http://sagepub.com
Peer Reviewed: Y
Page Count: 15
Publication Date: 2015
Document Type: Journal Articles
Reports - Research
Information Analyses
Descriptors: Autism, Pervasive Developmental Disorders, Behavior Problems, Repetition, Evaluation Methods, Interests, Test Validity, Literature Reviews, Questionnaires, Observation, Interviews, Antisocial Behavior, Check Lists, Severity (of Disability), Symptoms (Individual Disorders)
Assessment and Survey Identifiers: Aberrant Behavior Checklist
DOI: 10.1177/1362361313510069
ISSN: 1362-3613
Abstract: Restricted interests and repetitive behaviors vary widely in type, frequency, and intensity among children and adolescents with autism spectrum disorder. They can be stigmatizing and interfere with more constructive activities. Accordingly, restricted interests and repetitive behaviors may be a target of intervention. Several standardized instruments have been developed to assess restricted interests and repetitive behaviors in the autism spectrum disorder population, but the rigor of psychometric assessment is variable. This article evaluated the readiness of available measures for use as outcome measures in clinical trials. The Autism Speaks Foundation assembled a panel of experts to examine available instruments used to measure restricted interests and repetitive behaviors in youth with autism spectrum disorder. The panel held monthly conference calls and two face-to-face meetings over 14 months to develop and apply evaluative criteria for available instruments. Twenty-four instruments were evaluated and five were considered "appropriate with conditions" for use as outcome measures in clinical trials. Ideally, primary outcome measures should be relevant to the clinical target, be reliable and valid, and cover the symptom domain without being burdensome to subjects. The goal of the report was to promote consensus across funding agencies, pharmaceutical companies, and clinical investigators about advantages and disadvantages of existing outcome measures.
Abstractor: As Provided
Number of References: 62
Entry Date: 2014
Accession Number: EJ1047990
Database: ERIC
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Abstract:Restricted interests and repetitive behaviors vary widely in type, frequency, and intensity among children and adolescents with autism spectrum disorder. They can be stigmatizing and interfere with more constructive activities. Accordingly, restricted interests and repetitive behaviors may be a target of intervention. Several standardized instruments have been developed to assess restricted interests and repetitive behaviors in the autism spectrum disorder population, but the rigor of psychometric assessment is variable. This article evaluated the readiness of available measures for use as outcome measures in clinical trials. The Autism Speaks Foundation assembled a panel of experts to examine available instruments used to measure restricted interests and repetitive behaviors in youth with autism spectrum disorder. The panel held monthly conference calls and two face-to-face meetings over 14 months to develop and apply evaluative criteria for available instruments. Twenty-four instruments were evaluated and five were considered "appropriate with conditions" for use as outcome measures in clinical trials. Ideally, primary outcome measures should be relevant to the clinical target, be reliable and valid, and cover the symptom domain without being burdensome to subjects. The goal of the report was to promote consensus across funding agencies, pharmaceutical companies, and clinical investigators about advantages and disadvantages of existing outcome measures.
ISSN:1362-3613
DOI:10.1177/1362361313510069