Genetic Advances in Autism
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| Title: | Genetic Advances in Autism |
|---|---|
| Language: | English |
| Authors: | Thapar, Anita, Rutter, Michael |
| Source: | Journal of Autism and Developmental Disorders. Dec 2021 51(12):4321-4332. |
| Availability: | Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/ |
| Peer Reviewed: | Y |
| Page Count: | 12 |
| Publication Date: | 2021 |
| Document Type: | Journal Articles Reports - Evaluative |
| Descriptors: | Autism, Pervasive Developmental Disorders, Genetic Disorders, At Risk Persons, Clinical Diagnosis, Research |
| DOI: | 10.1007/s10803-020-04685-z |
| ISSN: | 0162-3257 |
| Abstract: | In the last 40 years, there has been a huge increase in autism genetics research and a rapidly growing number of discoveries. We now know autism is one of the most highly heritable disorders with negligible shared environmental contributions. Recent discoveries also show that rare variants of large effect size as well as small effect common gene variants all contribute to autism risk. These discoveries challenge traditional diagnostic boundaries and highlight huge heterogeneity in autism. In this review, we consider some of the key findings that are shaping current understanding of autism and what these discoveries mean for clinicians. |
| Abstractor: | As Provided |
| Entry Date: | 2021 |
| Accession Number: | EJ1315311 |
| Database: | ERIC |
| Abstract: | In the last 40 years, there has been a huge increase in autism genetics research and a rapidly growing number of discoveries. We now know autism is one of the most highly heritable disorders with negligible shared environmental contributions. Recent discoveries also show that rare variants of large effect size as well as small effect common gene variants all contribute to autism risk. These discoveries challenge traditional diagnostic boundaries and highlight huge heterogeneity in autism. In this review, we consider some of the key findings that are shaping current understanding of autism and what these discoveries mean for clinicians. |
|---|---|
| ISSN: | 0162-3257 |
| DOI: | 10.1007/s10803-020-04685-z |
