Genetic Advances in Autism
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| Title: | Genetic Advances in Autism |
|---|---|
| Language: | English |
| Authors: | Thapar, Anita, Rutter, Michael |
| Source: | Journal of Autism and Developmental Disorders. Dec 2021 51(12):4321-4332. |
| Availability: | Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/ |
| Peer Reviewed: | Y |
| Page Count: | 12 |
| Publication Date: | 2021 |
| Document Type: | Journal Articles Reports - Evaluative |
| Descriptors: | Autism, Pervasive Developmental Disorders, Genetic Disorders, At Risk Persons, Clinical Diagnosis, Research |
| DOI: | 10.1007/s10803-020-04685-z |
| ISSN: | 0162-3257 |
| Abstract: | In the last 40 years, there has been a huge increase in autism genetics research and a rapidly growing number of discoveries. We now know autism is one of the most highly heritable disorders with negligible shared environmental contributions. Recent discoveries also show that rare variants of large effect size as well as small effect common gene variants all contribute to autism risk. These discoveries challenge traditional diagnostic boundaries and highlight huge heterogeneity in autism. In this review, we consider some of the key findings that are shaping current understanding of autism and what these discoveries mean for clinicians. |
| Abstractor: | As Provided |
| Entry Date: | 2021 |
| Accession Number: | EJ1315311 |
| Database: | ERIC |
| FullText | Links: – Type: pdflink Url: https://content.ebscohost.com/cds/retrieve?content=AQICAHj0k_4E0hTGH8RJwT4gCJyBsGNe_WN95AvKlDbXJGqwxwG1ZAP3bH_rgjg16qKorZV1AAAA4zCB4AYJKoZIhvcNAQcGoIHSMIHPAgEAMIHJBgkqhkiG9w0BBwEwHgYJYIZIAWUDBAEuMBEEDPxnaoX0WkIABP-n-wIBEICBm2wWEqkFdr5IGTdGH5zHtOcoH2l4AZqFOAiVgJofsAgAV5eIwrGcY5SGJ4xYHpKF5Bv2rL3SrZxCZ7SfzlAGjZeXH9mZlfTtfN04S2Xur9tyZajUKCVL5B3k6gM5wXzJMnxuu8ioeWKf6R8NPYoJBHpa0L4y2oj1B9vr6HCCogD6Jx2gq8cbr-zWDOfNdf_BnoGNBjYwLRPQddg7 Text: Availability: 0 |
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| Header | DbId: eric DbLabel: ERIC An: EJ1315311 AccessLevel: 3 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Genetic Advances in Autism – Name: Language Label: Language Group: Lang Data: English – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Thapar%2C+Anita%22">Thapar, Anita</searchLink><br /><searchLink fieldCode="AR" term="%22Rutter%2C+Michael%22">Rutter, Michael</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="SO" term="%22Journal+of+Autism+and+Developmental+Disorders%22"><i>Journal of Autism and Developmental Disorders</i></searchLink>. Dec 2021 51(12):4321-4332. – Name: Avail Label: Availability Group: Avail Data: Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/ – Name: PeerReviewed Label: Peer Reviewed Group: SrcInfo Data: Y – Name: Pages Label: Page Count Group: Src Data: 12 – Name: DatePubCY Label: Publication Date Group: Date Data: 2021 – Name: TypeDocument Label: Document Type Group: TypDoc Data: Journal Articles<br />Reports - Evaluative – Name: Subject Label: Descriptors Group: Su Data: <searchLink fieldCode="DE" term="%22Autism%22">Autism</searchLink><br /><searchLink fieldCode="DE" term="%22Pervasive+Developmental+Disorders%22">Pervasive Developmental Disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+Disorders%22">Genetic Disorders</searchLink><br /><searchLink fieldCode="DE" term="%22At+Risk+Persons%22">At Risk Persons</searchLink><br /><searchLink fieldCode="DE" term="%22Clinical+Diagnosis%22">Clinical Diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Research%22">Research</searchLink> – Name: DOI Label: DOI Group: ID Data: 10.1007/s10803-020-04685-z – Name: ISSN Label: ISSN Group: ISSN Data: 0162-3257 – Name: Abstract Label: Abstract Group: Ab Data: In the last 40 years, there has been a huge increase in autism genetics research and a rapidly growing number of discoveries. We now know autism is one of the most highly heritable disorders with negligible shared environmental contributions. Recent discoveries also show that rare variants of large effect size as well as small effect common gene variants all contribute to autism risk. These discoveries challenge traditional diagnostic boundaries and highlight huge heterogeneity in autism. In this review, we consider some of the key findings that are shaping current understanding of autism and what these discoveries mean for clinicians. – Name: AbstractInfo Label: Abstractor Group: Ab Data: As Provided – Name: DateEntry Label: Entry Date Group: Date Data: 2021 – Name: AN Label: Accession Number Group: ID Data: EJ1315311 |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=eric&AN=EJ1315311 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10803-020-04685-z Languages: – Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 4321 Subjects: – SubjectFull: Autism Type: general – SubjectFull: Pervasive Developmental Disorders Type: general – SubjectFull: Genetic Disorders Type: general – SubjectFull: At Risk Persons Type: general – SubjectFull: Clinical Diagnosis Type: general – SubjectFull: Research Type: general Titles: – TitleFull: Genetic Advances in Autism Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Thapar, Anita – PersonEntity: Name: NameFull: Rutter, Michael IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Type: published Y: 2021 Identifiers: – Type: issn-print Value: 0162-3257 Numbering: – Type: volume Value: 51 – Type: issue Value: 12 Titles: – TitleFull: Journal of Autism and Developmental Disorders Type: main |
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