Visceral Adipose Tissue Accumulation in Children with Obesity and Co-Occurring ADHD: A Case-Control Analysis of Body Fat Distribution Patterns

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Bibliographic Details
Title: Visceral Adipose Tissue Accumulation in Children with Obesity and Co-Occurring ADHD: A Case-Control Analysis of Body Fat Distribution Patterns
Language: English
Authors: Muhan Li (ORCID 0000-0001-6327-9983), Shijie Li, Yan Hu, Chenlu Yang, Aimin Liang
Source: Journal of Attention Disorders. 2026 30(6):747-756.
Availability: SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: https://sagepub.com
Peer Reviewed: Y
Page Count: 10
Publication Date: 2026
Document Type: Journal Articles
Reports - Research
Descriptors: Attention Deficit Hyperactivity Disorder, Obesity, Human Body, Children, Preadolescents, Body Composition, Metabolism, Individual Characteristics, Foreign Countries, Comorbidity
Geographic Terms: China (Beijing)
DOI: 10.1177/10870547251397010
ISSN: 1087-0547
1557-1246
Abstract: Objective: ADHD and obesity frequently co-occur in children, yet differences in visceral adipose tissue (VAT) distribution between co-occurring ADHD + Obesity and obesity alone are incompletely characterized. This study compared depot-specific adiposity between these groups. Methods: This cross-sectional analysis (December 2022-2024, Beijing Children's Hospital) included 306 children (6-12 years) stratified into: ADHD + Obesity (n = 65), obesity-only (n = 77), and Control (n = 164). Body composition was assessed using bioelectrical impedance. Group comparisons for depot-specific adiposity and metabolic markers were performed using multivariable linear regression, adjusting for age, sex, and BMI z-score. Results: The ADHD + Obesity group exhibited significantly greater visceral adiposity than the Obesity-only group, as reflected by a 16.84 cm2 larger visceral fat area (VFA) and a 1.03 kg/m2 higher fat mass index (FMI). The ADHD + Obesity group also showed a more adverse metabolic profile, including elevated liver enzymes and fasting glucose. Conclusion: Excess visceral adiposity represents a distinct phenotypic feature of ADHD + Obesity. These findings support the need for integrated clinical management addressing both neurobehavioral and metabolic domains and inform future mechanistic investigations.
Abstractor: As Provided
Entry Date: 2026
Accession Number: EJ1504250
Database: ERIC
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Description
Abstract:Objective: ADHD and obesity frequently co-occur in children, yet differences in visceral adipose tissue (VAT) distribution between co-occurring ADHD + Obesity and obesity alone are incompletely characterized. This study compared depot-specific adiposity between these groups. Methods: This cross-sectional analysis (December 2022-2024, Beijing Children's Hospital) included 306 children (6-12 years) stratified into: ADHD + Obesity (n = 65), obesity-only (n = 77), and Control (n = 164). Body composition was assessed using bioelectrical impedance. Group comparisons for depot-specific adiposity and metabolic markers were performed using multivariable linear regression, adjusting for age, sex, and BMI z-score. Results: The ADHD + Obesity group exhibited significantly greater visceral adiposity than the Obesity-only group, as reflected by a 16.84 cm2 larger visceral fat area (VFA) and a 1.03 kg/m2 higher fat mass index (FMI). The ADHD + Obesity group also showed a more adverse metabolic profile, including elevated liver enzymes and fasting glucose. Conclusion: Excess visceral adiposity represents a distinct phenotypic feature of ADHD + Obesity. These findings support the need for integrated clinical management addressing both neurobehavioral and metabolic domains and inform future mechanistic investigations.
ISSN:1087-0547
1557-1246
DOI:10.1177/10870547251397010