Amisulpride versus Bromocriptine in Infantile Autism: A Controlled Crossover Comparative Study of Two Drugs with Opposite Effects on Dopaminergic Function.

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Bibliographic Details
Title: Amisulpride versus Bromocriptine in Infantile Autism: A Controlled Crossover Comparative Study of Two Drugs with Opposite Effects on Dopaminergic Function.
Language: English
Authors: Dollfus, Sonia
Source: Journal of Autism and Developmental Disorders. Mar 1992 22(1):46-60.
Peer Reviewed: Y
Page Count: 15
Publication Date: 1992
Intended Audience: Researchers
Document Type: Journal Articles
Reports - Research
Descriptors: Attention Control, Autism, Behavior Patterns, Children, Drug Therapy, Hyperactivity, Medical Research, Medical Services, Outcomes of Treatment, Severe Mental Retardation, Young Children
ISSN: 0162-3257
Abstract: This study compared the clinical efficacy of a dopaminergic antagonist (amisulpride) and a dopaminergic agonist (bromocriptine) with 9 children (ages 4-13) with autism and probable severe mental retardation. The amisulpride acted preferentially on specific autism symptoms and the bromocriptine on motor hyperactivity and attention symptoms. (Author/DB)
Journal Code: CIJDEC1992
Entry Date: 1992
Accession Number: EJ448658
Database: ERIC
Description
Abstract:This study compared the clinical efficacy of a dopaminergic antagonist (amisulpride) and a dopaminergic agonist (bromocriptine) with 9 children (ages 4-13) with autism and probable severe mental retardation. The amisulpride acted preferentially on specific autism symptoms and the bromocriptine on motor hyperactivity and attention symptoms. (Author/DB)
ISSN:0162-3257