Bibliographic Details
| Title: |
Seroprevalence and Trends of HTLV-1/2 among Blood Donors of Santo Domingo, Dominican Republic, 2012-2017. |
| Alternate Title: |
Seroprevalencia y tendencias de HTLV-1/2 en los donantes de sangre de Santo Domingo, República Dominicana, 2012-2017. |
| Authors: |
Eusebio-Ponce, Emiliana1,2, Javier Candel, Francisco2,3, Paulino-Ramirez, Robert1, Serrano-García, Irene4, Anguita, Eduardo2,5 eduardo.anguita@salud.madrid.org |
| Source: |
Revista Española de Quimioterapia. Feb2021, Vol. 34 Issue 1, p44-50. 7p. |
| Subjects: |
SEROPREVALENCE, BLOOD donors, ENDEMIC diseases, BLOOD banks |
| Geographic Terms: |
DOMINICAN Republic |
| Abstract (English): |
Objectives. Being a Caribbean country, the Dominican Republic is considered endemic for HTLV-1. Viral screening in blood banks is recommended for this blood borne infection. The purpose of this work is to analyze the seroprevalence and trends of HTLV-1/2 in the Dominican Republic blood donors; it is focused on Santo Domingo, the capital of the country, which has the largest blood donation activity. We also aim at comparing our findings with published data from neighboring countries. Patients and methods. We performed a retrospective cross-sectional study of 10 blood centers of Santo Domingo, which reported HTLV and the other blood-transmitted infections in full. They represent more than 40% of the province's blood donations. Annual seroprevalence of HTLV-1/2, period prevalence (2012-2017), and time trend were determined. Results. A total of 352,960 blood donations were evaluated. The HTLV-1/2 period prevalence was 0.26% (929/352,960) (95% CI: 0.24-0.28%). We also found a marked predominance of replacement donation (90.4%) in comparison to voluntary contributions (9.6%). Therefore, this blood donor study may provide clues on the general prevalence of the infection. Conclusions. Seroprevalence of HTLV-1/2 in blood donors of Santo Domingo, Dominican Republic, showed a relatively low and steady trend in the studied period. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
Objetivo. Como país caribeño, la República Dominicana es considerada endémica para HTLV-1. El propósito de este trabajo es analizar la seroprevalencia y la tendencia del HTLV-1/2 en donantes de Santo Domingo, que al ser la capital concentra la mayoría de las donaciones. También pretendemos comparar nuestros hallazgos con los datos de los países vecinos. Pacientes y métodos. Hemos realizado un estudio transversal retrospectivo de los 10 centros de transfusión de Santo Domingo que comunicaron la detección de HTLV y las otras infecciones de transmisión sanguínea en su totalidad, que representan más del 40% de las donaciones de la provincia. Se determinó la seroprevalencia anual de HTLV-1/2, la prevalencia del período (2012-2017) y la tendencia temporal. Resultados. Se evaluaron un total de 352.960 donaciones. La prevalencia de HTLV-1/2 en el período estudiado fue del 0,26% (929/352.960) (IC del 95%: 0,24-0,28%). Encontramos un marcado predominio de la donación de reemplazo en comparación con la voluntaria. Por lo tanto, este estudio puede proporcionar claves sobre la prevalencia general de la infección. Conclusiones. La seroprevalencia de HTLV-1/2 en donantes de sangre de Santo Domingo, República Dominicana, ha sido relativamente baja y estable en el periodo estudiado. [ABSTRACT FROM AUTHOR] |
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| Database: |
MedicLatina |
