Bibliographic Details
| Title: |
Tocilizumab in a Patient With Tophaceous Gout Resistant to Treatment. |
| Alternate Title: |
Tocilizumab en paciente con gota tofácea severa refractaria al tratamiento. |
| Authors: |
Pinto, Jessica L.1, Mora, Gloria E.1, Fernández-Avila, Daniel G.1 danielfernandezmd@gmail.com, Gutiérrez, Juan M.1, Díaz, María C.1 |
| Source: |
Reumatología Clínica. may/jun2013, Vol. 9 Issue 3, p178-180. 3p. |
| Subjects: |
GOUT treatment, RHEUMATOID arthritis treatment, JOINT injuries, ADRENOCORTICAL hormones, DRUG resistance, INFLAMMATION |
| Abstract (English): |
Gout is a disease characterized by acute episodes of pain, which occurs as the result of monosodic urate crystal deposit in the joint and periarticular tissue. In some cases, gout behaves as a severe inflammatory arthopathy that is difficult to manage, generating structural joint damage and functional impairment. We report the case of a 44 years old man with gouty arthritis for 12 years, not responding to NSAIDs, alopurinol, colchicine or corticosteroids. Tocilizumab was started with favorable clinical and laboratory results after treatment. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): |
La gota es una enfermedad que se caracteriza por episodios agudos de dolor como consecuencia del depósito de cristales de urato monosódico en las articulaciones y en el tejido periarticular. En algunos casos, la gota se comporta como una artropatía inflamatoria severa de difícil manejo, generándose dano estructural articular y alteración funcional secundaria. Presentamos el caso de un hombre de 44 anos con artritis gotosa tofácea severa de 12 años de evolución, sin respuesta al manejo con AINE, alopurinol, colchicina y corticoides, a quien se inició tratamiento con tocilizumab, con favorable respuesta clínica y paraclínica. [ABSTRACT FROM AUTHOR] |
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| Database: |
MedicLatina |
