Tocilizumab in a Patient With Tophaceous Gout Resistant to Treatment.

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Title: Tocilizumab in a Patient With Tophaceous Gout Resistant to Treatment.
Alternate Title: Tocilizumab en paciente con gota tofácea severa refractaria al tratamiento.
Authors: Pinto, Jessica L.1, Mora, Gloria E.1, Fernández-Avila, Daniel G.1 danielfernandezmd@gmail.com, Gutiérrez, Juan M.1, Díaz, María C.1
Source: Reumatología Clínica. may/jun2013, Vol. 9 Issue 3, p178-180. 3p.
Subjects: GOUT treatment, RHEUMATOID arthritis treatment, JOINT injuries, ADRENOCORTICAL hormones, DRUG resistance, INFLAMMATION
Abstract (English): Gout is a disease characterized by acute episodes of pain, which occurs as the result of monosodic urate crystal deposit in the joint and periarticular tissue. In some cases, gout behaves as a severe inflammatory arthopathy that is difficult to manage, generating structural joint damage and functional impairment. We report the case of a 44 years old man with gouty arthritis for 12 years, not responding to NSAIDs, alopurinol, colchicine or corticosteroids. Tocilizumab was started with favorable clinical and laboratory results after treatment. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): La gota es una enfermedad que se caracteriza por episodios agudos de dolor como consecuencia del depósito de cristales de urato monosódico en las articulaciones y en el tejido periarticular. En algunos casos, la gota se comporta como una artropatía inflamatoria severa de difícil manejo, generándose dano estructural articular y alteración funcional secundaria. Presentamos el caso de un hombre de 44 anos con artritis gotosa tofácea severa de 12 años de evolución, sin respuesta al manejo con AINE, alopurinol, colchicina y corticoides, a quien se inició tratamiento con tocilizumab, con favorable respuesta clínica y paraclínica. [ABSTRACT FROM AUTHOR]
Copyright of Reumatología Clínica is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
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  Data: Tocilizumab in a Patient With Tophaceous Gout Resistant to Treatment.
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  Data: Tocilizumab en paciente con gota tofácea severa refractaria al tratamiento.
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  Data: <searchLink fieldCode="AR" term="%22Pinto%2C+Jessica+L%2E%22">Pinto, Jessica L.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Mora%2C+Gloria+E%2E%22">Mora, Gloria E.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Fernández-Avila%2C+Daniel+G%2E%22">Fernández-Avila, Daniel G.</searchLink><relatesTo>1</relatesTo><i> danielfernandezmd@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Gutiérrez%2C+Juan+M%2E%22">Gutiérrez, Juan M.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Díaz%2C+María+C%2E%22">Díaz, María C.</searchLink><relatesTo>1</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Reumatología+Clínica%22">Reumatología Clínica</searchLink>. may/jun2013, Vol. 9 Issue 3, p178-180. 3p.
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  Data: <searchLink fieldCode="DE" term="%22GOUT+treatment%22">GOUT treatment</searchLink><br /><searchLink fieldCode="DE" term="%22RHEUMATOID+arthritis+treatment%22">RHEUMATOID arthritis treatment</searchLink><br /><searchLink fieldCode="DE" term="%22JOINT+injuries%22">JOINT injuries</searchLink><br /><searchLink fieldCode="DE" term="%22ADRENOCORTICAL+hormones%22">ADRENOCORTICAL hormones</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+resistance%22">DRUG resistance</searchLink><br /><searchLink fieldCode="DE" term="%22INFLAMMATION%22">INFLAMMATION</searchLink>
– Name: Abstract
  Label: Abstract (English)
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  Data: Gout is a disease characterized by acute episodes of pain, which occurs as the result of monosodic urate crystal deposit in the joint and periarticular tissue. In some cases, gout behaves as a severe inflammatory arthopathy that is difficult to manage, generating structural joint damage and functional impairment. We report the case of a 44 years old man with gouty arthritis for 12 years, not responding to NSAIDs, alopurinol, colchicine or corticosteroids. Tocilizumab was started with favorable clinical and laboratory results after treatment. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: La gota es una enfermedad que se caracteriza por episodios agudos de dolor como consecuencia del depósito de cristales de urato monosódico en las articulaciones y en el tejido periarticular. En algunos casos, la gota se comporta como una artropatía inflamatoria severa de difícil manejo, generándose dano estructural articular y alteración funcional secundaria. Presentamos el caso de un hombre de 44 anos con artritis gotosa tofácea severa de 12 años de evolución, sin respuesta al manejo con AINE, alopurinol, colchicina y corticoides, a quien se inició tratamiento con tocilizumab, con favorable respuesta clínica y paraclínica. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Reumatología Clínica is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1016/j.reuma.2012.06.009
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      – Code: eng
        Text: English
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        PageCount: 3
        StartPage: 178
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      – SubjectFull: GOUT treatment
        Type: general
      – SubjectFull: RHEUMATOID arthritis treatment
        Type: general
      – SubjectFull: JOINT injuries
        Type: general
      – SubjectFull: ADRENOCORTICAL hormones
        Type: general
      – SubjectFull: DRUG resistance
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      – SubjectFull: INFLAMMATION
        Type: general
    Titles:
      – TitleFull: Tocilizumab in a Patient With Tophaceous Gout Resistant to Treatment.
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            NameFull: Pinto, Jessica L.
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            NameFull: Mora, Gloria E.
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            NameFull: Díaz, María C.
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              M: 05
              Text: may/jun2013
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              Y: 2013
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