PEG-pHPMAm-based polymeric micelles loaded with doxorubicin-prodrugs in combination antitumor therapy with oncolytic vaccinia viruses.

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Title: PEG-pHPMAm-based polymeric micelles loaded with doxorubicin-prodrugs in combination antitumor therapy with oncolytic vaccinia viruses.
Authors: Ruiz-Hernández E; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Hess M; Department of Biochemistry, Biocenter, University of Würzburg, 97074 Würzburg, Germany., Melen GJ; Department of Hematooncology & Stem Cell Transplantation Hospital Infantil Universitario Niño Jesús, Madrid, Spain., Theek B; Department of Experimental Molecular Imaging, University Clinic and Helmholtz Center for Biomedical Engineering, Aachen, Germany., Talelli M; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.; Department of Inorganic and Bioinorganic Chemistry, Facultad de Farmacia, Universidad Complutense de Madrid, Spain., Shi Y; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Ozbakir B; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Teunissen EA; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Ramírez M; Department of Hematooncology & Stem Cell Transplantation Hospital Infantil Universitario Niño Jesús, Madrid, Spain., Moeckel D; Department of Experimental Molecular Imaging, University Clinic and Helmholtz Center for Biomedical Engineering, Aachen, Germany., Kiessling F; Department of Experimental Molecular Imaging, University Clinic and Helmholtz Center for Biomedical Engineering, Aachen, Germany., Storm G; Department of Controlled Drug Delivery, Targeted Therapeutics Section, University of Twente and MIRA Institute for Biomedical Engineering and Technical Medicine, Enschede, The Netherlands., Scheeren HW; Department of Organic Chemistry, Radboud Univ Nijmegen, Heyendaalse weg 135, 6525 AJ Nijmegen, The Netherlands., Hennink WE; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Szalay AA; Department of Biochemistry, Biocenter, University of Würzburg, 97074 Würzburg, Germany.; Genelux Corporation, San Diego Science Center, San Diego, CA 92109, USA.; Department of Radiation Oncology, Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA., Stritzker J; Department of Biochemistry, Biocenter, University of Würzburg, 97074 Würzburg, Germany.; Genelux Corporation, San Diego Science Center, San Diego, CA 92109, USA., Lammers T; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.; Department of Experimental Molecular Imaging, University Clinic and Helmholtz Center for Biomedical Engineering, Aachen, Germany.; Department of Controlled Drug Delivery, Targeted Therapeutics Section, University of Twente and MIRA Institute for Biomedical Engineering and Technical Medicine, Enschede, The Netherlands.
Source: Polymer chemistry [Polym Chem] 2014 Mar 07 (5), pp. 1674-1681.
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101562526 Publication Model: Print Cited Medium: Print ISSN: 1759-9954 (Print) Linking ISSN: 17599954 NLM ISO Abbreviation: Polym Chem Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1759-9954
DOI:10.1039/C3PY01097J