Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors.

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Title: Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors.
Authors: Baur R; Institute for Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland (R.Ba., E.S.); Institute of Parasitology, Macdonald College, McGill University, Ste Anne de Bellevue, Quebec, Canada (R.Be., L.R.); and Novartis Centre de Recherche Santé Animale, Saint-Aubin, Switzerland (L.R.)., Beech R; Institute for Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland (R.Ba., E.S.); Institute of Parasitology, Macdonald College, McGill University, Ste Anne de Bellevue, Quebec, Canada (R.Be., L.R.); and Novartis Centre de Recherche Santé Animale, Saint-Aubin, Switzerland (L.R.)., Sigel E; Institute for Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland (R.Ba., E.S.); Institute of Parasitology, Macdonald College, McGill University, Ste Anne de Bellevue, Quebec, Canada (R.Be., L.R.); and Novartis Centre de Recherche Santé Animale, Saint-Aubin, Switzerland (L.R.)., Rufener L; Institute for Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland (R.Ba., E.S.); Institute of Parasitology, Macdonald College, McGill University, Ste Anne de Bellevue, Quebec, Canada (R.Be., L.R.); and Novartis Centre de Recherche Santé Animale, Saint-Aubin, Switzerland (L.R.) lucien.rufener@novartis.com.
Source: Molecular pharmacology [Mol Pharmacol] 2015 Jan; Vol. 87 (1), pp. 96-102. Date of Electronic Publication: 2014 Oct 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1521-0111
DOI:10.1124/mol.114.095653