Fumarate induces redox-dependent senescence by modifying glutathione metabolism.

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Title: Fumarate induces redox-dependent senescence by modifying glutathione metabolism.
Authors: Zheng L; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK., Cardaci S; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK., Jerby L; The Blavatnik School of Computer Science-Tel Aviv University, Tel Aviv 69978, Israel., MacKenzie ED; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK., Sciacovelli M; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge CB2 0XZ, UK., Johnson TI; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge CB2 0XZ, UK., Gaude E; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge CB2 0XZ, UK., King A; Institute of Cancer Sciences, University of Glasgow, Switchback Road, Glasgow G61 1BD, UK., Leach JD; School of Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow G61 1QH, UK., Edrada-Ebel R; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 16 Richmond Street, Glasgow G1 1XQ, UK., Hedley A; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK., Morrice NA; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK., Kalna G; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK., Blyth K; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK., Ruppin E; 1] The Blavatnik School of Computer Science-Tel Aviv University, Tel Aviv 69978, Israel [2] The Sackler School of Medicine-Tel Aviv University, Tel Aviv 69978, Israel., Frezza C; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge CB2 0XZ, UK., Gottlieb E; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
Source: Nature communications [Nat Commun] 2015 Jan 23; Vol. 6, pp. 6001. Date of Electronic Publication: 2015 Jan 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/ncomms7001