SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas.

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Title: SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas.
Authors: Le Loarer F; Cancer Research Center of Lyon, INSERM U1052, Lyon, France.; Centre Leon Berard, Department of Pathology, Lyon, France.; Université Claude Bernard Lyon 1, Lyon, France., Watson S; Genetics and Biology of Cancer Unit, Institut Curie Research Center, Paris Sciences et Lettres Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France., Pierron G; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France., de Montpreville VT; Centre Chirurgical Marie Lannelongue, Department of Pathology, Le Plessis Robinson, France., Ballet S; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France., Firmin N; Institut de Cancerologie de Montpellier, Department of Oncology, Montpellier, France., Auguste A; Gustave Roussy, INSERM U981, Villejuif, France., Pissaloux D; Centre Leon Berard, Department of Pathology, Lyon, France., Boyault S; Centre Leon Berard, Department of Genetics, Lyon, France., Paindavoine S; Centre Leon Berard, Department of Pathology, Lyon, France., Dechelotte PJ; Centre Hospitalier Universitaire (CHU) de Clermont Ferrand, Department of Pathology, Clermont Ferrand, France., Besse B; Gustave Roussy, Department of Cancer Medicine, Villejuif, France.; Université Paris Sud, Paris, France., Vignaud JM; CHU Nancy, Department of Pathology, Nancy, France., Brevet M; Université Claude Bernard Lyon 1, Lyon, France.; Hospices Civils de Lyon, Groupement Hospitalier Est, Department of Pathology, Lyon, France., Fadel E; Université Paris Sud, Paris, France.; Centre Chirurgical Marie Lannelongue, Department of Thoracic Surgery, Le Plessis Robinson, France., Richer W; Genetics and Biology of Cancer Unit, Institut Curie Research Center, Paris Sciences et Lettres Research University, Paris, France.; Site de Recherche Intégrée en Cancérologie (SiRIC) Institut Curie, Recherche Translationelle en Oncologie Pédiatrique (RTOP), Paris, France., Treilleux I; Centre Leon Berard, Department of Pathology, Lyon, France., Masliah-Planchon J; INSERM U830, Institut Curie Research Center, Paris, France.; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France., Devouassoux-Shisheboran M; Hospices Civils de Lyon, Hôpital de la Croix Rousse, Department of Pathology, Lyon, France., Zalcman G; CHU Caen, Department of Pneumology and Thoracic Oncology, Caen, France.; Unité Mixte de Recherche (UMR) INSERM U186, Université Caen-Basse Normandie, Caen, France., Allory Y; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Henri Mondor, Plateforme de Ressources Biologiques, Creteil, France.; Université Paris-Est, Créteil, France.; INSERM U955, Institut Mondor de Recherche Biomédicale, Créteil, France., Bourdeaut F; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France.; Institut Curie, Département d'Oncologie Pédiatrique, Paris, France., Thivolet-Bejui F; Université Claude Bernard Lyon 1, Lyon, France.; Hospices Civils de Lyon, Groupement Hospitalier Est, Department of Pathology, Lyon, France., Ranchere-Vince D; Centre Leon Berard, Department of Pathology, Lyon, France., Girard N; Université Claude Bernard Lyon 1, Lyon, France.; Hospices Civils de Lyon, Groupement Hospitalier Est, Department of Respiratory Medicine, Lyon, France., Lantuejoul S; CHU Grenoble, Department of Pathology, Grenoble, France.; Université de Grenoble Joseph Fourier, Grenoble, France., Galateau-Sallé F; CHU Caen, Department of Pathology, Caen, France.; INSERM U1086, Caen, France., Coindre JM; Institut Bergonie, Department of Pathology, Bordeaux, France.; Université Bordeaux 2, Bordeaux, France., Leary A; Gustave Roussy, INSERM U981, Villejuif, France.; Gustave Roussy, Department of Cancer Medicine, Villejuif, France., Delattre O; Genetics and Biology of Cancer Unit, Institut Curie Research Center, Paris Sciences et Lettres Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France.; Institut Curie Hospital Group, Unité de Génétique Somatique, Paris, France., Blay JY; Cancer Research Center of Lyon, INSERM U1052, Lyon, France.; Université Claude Bernard Lyon 1, Lyon, France.; Centre Leon Berard, Department of Oncology, Lyon, France., Tirode F; Genetics and Biology of Cancer Unit, Institut Curie Research Center, Paris Sciences et Lettres Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France.
Source: Nature genetics [Nat Genet] 2015 Oct; Vol. 47 (10), pp. 1200-5. Date of Electronic Publication: 2015 Sep 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1546-1718
DOI:10.1038/ng.3399