CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease.

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Title: CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease.
Authors: Hoh BL; Departments of 1 Neurosurgery and., Gong Y; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida; and, McDonough CW; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida; and, Waters MF; Neurology, and., Royster AJ; Departments of 1 Neurosurgery and., Sheehan TO; Neurology, and., Burkley B; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida; and, Langaee TY; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida; and, Mocco J; Departments of 4 Neurosurgery., Zuckerman SL; Departments of 4 Neurosurgery., Mummareddy N; Departments of 4 Neurosurgery., Stephens ML 2nd; Departments of 4 Neurosurgery., Ingram C; Medicine, and., Shaffer CM; Medicine, and., Denny JC; Medicine, and., Brilliant MH; Center for Human Genetics Research and., Kitchner TE; Center for Human Genetics Research and., Linneman JG; Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, Wisconsin., Roden DM; Medicine, and.; Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, and., Johnson JA; Division of Cardiovascular Medicine, College of Medicine, and.; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida; and
Source: Journal of neurosurgery [J Neurosurg] 2016 Jun; Vol. 124 (6), pp. 1746-51. Date of Electronic Publication: 2015 Nov 20.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: American Association of Neurological Surgeons Country of Publication: United States NLM ID: 0253357 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-0693 (Electronic) Linking ISSN: 00223085 NLM ISO Abbreviation: J Neurosurg Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1933-0693
DOI:10.3171/2015.6.JNS15795