Leptin, BMI, and a Metabolic Gene Expression Signature Associated with Clinical Outcome to VEGF Inhibition in Colorectal Cancer.

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Title: Leptin, BMI, and a Metabolic Gene Expression Signature Associated with Clinical Outcome to VEGF Inhibition in Colorectal Cancer.
Authors: Pommier AJ; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK; Centre d'Immunologie Pierre Fabre, 5 Avenue Napoléon III, 74160 Saint-Julien-en-Genevois, France., Farren M; Cancer Research Technology, Angel Building, St. John Street, London EC1V 4AD, UK., Patel B; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Wappett M; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Michopoulos F; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Smith NR; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Kendrew J; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Frith J; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Huby R; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Eberlein C; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Campbell H; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Womack C; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Smith PD; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Robertson J; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Morgan S; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Critchlow SE; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Barry ST; AstraZeneca, Oncology iMED, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK. Electronic address: simon.t.barry@astrazeneca.com.
Source: Cell metabolism [Cell Metab] 2016 Jan 12; Vol. 23 (1), pp. 77-93. Date of Electronic Publication: 2015 Nov 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1932-7420
DOI:10.1016/j.cmet.2015.10.015