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MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression.

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Title: MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression.
Authors: Paugh SW; Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Coss DR; High Performance Computing Facility, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Bao J; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Laudermilk LT; Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Grace CR; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Ferreira AM; High Performance Computing Facility, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Waddell MB; Molecular Interaction Analysis Laboratory, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Ridout G; Functional Genomics Laboratory, Hartwell Center for Bioinformatics & Biotechnology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Naeve D; Functional Genomics Laboratory, Hartwell Center for Bioinformatics & Biotechnology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Leuze M; Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America., LoCascio PF; Doctoral Training Centre, University of Oxford, Oxford, United Kingdom., Panetta JC; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Wilkinson MR; Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Pui CH; Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Naeve CW; Department of Information Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Uberbacher EC; Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America., Bonten EJ; Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America., Evans WE; Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.
Source: PLoS computational biology [PLoS Comput Biol] 2016 Feb 04; Vol. 12 (2), pp. e1004744. Date of Electronic Publication: 2016 Feb 04 (Print Publication: 2016).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1553-7358
DOI:10.1371/journal.pcbi.1004744