Quantitating drug-target engagement in single cells in vitro and in vivo.

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Bibliographic Details
Title: Quantitating drug-target engagement in single cells in vitro and in vivo.
Authors: Dubach JM; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Kim E; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Yang K; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Cuccarese M; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Giedt RJ; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Meimetis LG; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Vinegoni C; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Weissleder R; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA.
Source: Nature chemical biology [Nat Chem Biol] 2017 Feb; Vol. 13 (2), pp. 168-173. Date of Electronic Publication: 2016 Dec 05.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1552-4469
DOI:10.1038/nchembio.2248