Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer.

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Title: Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer.
Authors: Magnani L; Department of Surgery and Cancer, Imperial College London, London, UK., Frige G; Department of Experimental Oncology, European Institute of Oncology Milan, Italy., Gadaleta RM; Department of Surgery and Cancer, Imperial College London, London, UK., Corleone G; Department of Surgery and Cancer, Imperial College London, London, UK., Fabris S; Hematology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, IT., Kempe MH; Swammerdam Institute for Life Sciences, University of Amsterdam., Verschure PJ; Swammerdam Institute for Life Sciences, University of Amsterdam., Barozzi I; Genomics Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA, USA., Vircillo V; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende (CS), Italy., Hong SP; Department of Surgery and Cancer, Imperial College London, London, UK., Perone Y; Department of Surgery and Cancer, Imperial College London, London, UK., Saini M; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), and Institute for Stem Cell Technology and Experimental Medicine GmbH, Heidelberg, Germany., Trumpp A; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), and Institute for Stem Cell Technology and Experimental Medicine GmbH, Heidelberg, Germany., Viale G; Division of Pathology, European Institute of Oncology and University of Milan, School of Medicine, Milan, Italy., Neri A; Hematology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, IT.; Department of Oncology and Hemato-oncology, University of Milano, Milan, IT., Ali S; Department of Surgery and Cancer, Imperial College London, London, UK., Colleoni MA; Division of Medical Senology, European Institute of Oncology, IEO, Milan, Italy., Pruneri G; Division of Pathology, European Institute of Oncology and University of Milan, School of Medicine, Milan, Italy., Minucci S; Department of Experimental Oncology, European Institute of Oncology Milan, Italy.; Department of Biosciences, University of Milano, Milan, IT.
Source: Nature genetics [Nat Genet] 2017 Mar; Vol. 49 (3), pp. 444-450. Date of Electronic Publication: 2017 Jan 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1546-1718
DOI:10.1038/ng.3773