Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects.

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Title: Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects.
Authors: Lucanic M; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Plummer WT; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Chen E; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Harke J; Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon 97403, USA., Foulger AC; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Onken B; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Coleman-Hulbert AL; Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon 97403, USA., Dumas KJ; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Guo S; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Johnson E; Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon 97403, USA., Bhaumik D; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Xue J; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Crist AB; Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon 97403, USA., Presley MP; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Harinath G; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Sedore CA; Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon 97403, USA., Chamoli M; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Kamat S; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Chen MK; Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon 97403, USA., Angeli S; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Chang C; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Willis JH; Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon 97403, USA., Edgar D; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Royal MA; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Chao EA; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Patel S; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Garrett T; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Ibanez-Ventoso C; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Hope J; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Kish JL; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Guo M; Division of Aging Biology, National Institute on Aging, 7201 Wisconsin Avenue, Bethesda, Maryland 20892-9205, USA., Lithgow GJ; The Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, California 94945, USA., Driscoll M; Nelson Biological Laboratories, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA., Phillips PC; Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon 97403, USA.
Source: Nature communications [Nat Commun] 2017 Feb 21; Vol. 8, pp. 14256. Date of Electronic Publication: 2017 Feb 21.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/ncomms14256