View in EDS

SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage.

Saved in:
Bibliographic Details
Title: SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage.
Authors: Jangi M; Computational Biology & Genomics, Biogen, Cambridge, MA 02142., Fleet C; Computational Biology & Genomics, Biogen, Cambridge, MA 02142., Cullen P; Computational Biology & Genomics, Biogen, Cambridge, MA 02142., Gupta SV; Computational Biology & Genomics, Biogen, Cambridge, MA 02142., Mekhoubad S; Stem Cell Research, Biogen, Cambridge, MA 02142., Chiao E; Stem Cell Research, Biogen, Cambridge, MA 02142., Allaire N; Computational Biology & Genomics, Biogen, Cambridge, MA 02142., Bennett CF; Neuroscience Drug Discovery, Ionis Pharmaceuticals, Carlsbad, CA 92008., Rigo F; Neuroscience Drug Discovery, Ionis Pharmaceuticals, Carlsbad, CA 92008., Krainer AR; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724., Hurt JA; Computational Biology & Genomics, Biogen, Cambridge, MA 02142., Carulli JP; Computational Biology & Genomics, Biogen, Cambridge, MA 02142; john.carulli@biogen.com john.staropoli@biogen.com., Staropoli JF; Rare Disease, Biogen, Cambridge, MA 02142 john.carulli@biogen.com john.staropoli@biogen.com.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Mar 21; Vol. 114 (12), pp. E2347-E2356. Date of Electronic Publication: 2017 Mar 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.1613181114