Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.

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Title: Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.
Authors: Folkersen L; Department of Systems Biology, Technical University of Denmark, Copenhagen, Denmark.; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Fauman E; Pfizer Worldwide Research & Development, Cambridge, Massachusetts, United States of America., Sabater-Lleal M; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Frånberg M; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Baldassarre D; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Veglia F; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Humphries SE; British Heart Foundation Laboratories, University College of London, Department of Medicine, Rayne Building, London, United Kingdom., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, and Department of Cardiology, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden., Smit AJ; Department of Medicine, University Medical Center Groningen, Groningen, the Netherlands., Giral P; Assistance Publique - Hopitaux de Paris; Service Endocrinologie-Metabolisme, Groupe Hôpitalier Pitie-Salpetriere, Unités de Prévention Cardiovasculaire, Paris, France., Kurl S; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, Kuopio, Finland., Mannarino E; Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy., Enroth S; Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala, Uppsala University, Uppsala, Sweden., Johansson Å; Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala, Uppsala University, Uppsala, Sweden., Enroth SB; Department of Internal Medicine, Uppsala University Hospital, Uppsala, Sweden., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lind L; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lindgren C; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom., Giedraitis V; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Silveira A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Franco-Cereceda A; Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Tremoli E; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala, Uppsala University, Uppsala, Sweden., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, United States of America., Brunak S; Department of Systems Biology, Technical University of Denmark, Copenhagen, Denmark., Eriksson P; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Ziemek D; Pfizer Worldwide Research & Development, Cambridge, Massachusetts, United States of America., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Mälarstig A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Pfizer Worldwide Research and Development, Stockholm, Sweden.
Corporate Authors: IMPROVE study group
Source: PLoS genetics [PLoS Genet] 2017 Apr 03; Vol. 13 (4), pp. e1006706. Date of Electronic Publication: 2017 Apr 03 (Print Publication: 2017).
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
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  Data: Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.
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  Data: <searchLink fieldCode="AU" term="%22Folkersen+L%22">Folkersen L</searchLink>; Department of Systems Biology, Technical University of Denmark, Copenhagen, Denmark.; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Fauman+E%22">Fauman E</searchLink>; Pfizer Worldwide Research & Development, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Sabater-Lleal+M%22">Sabater-Lleal M</searchLink>; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Strawbridge+RJ%22">Strawbridge RJ</searchLink>; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Frånberg+M%22">Frånberg M</searchLink>; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Sennblad+B%22">Sennblad B</searchLink>; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Baldassarre+D%22">Baldassarre D</searchLink>; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Veglia+F%22">Veglia F</searchLink>; Centro Cardiologico Monzino, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Humphries+SE%22">Humphries SE</searchLink>; British Heart Foundation Laboratories, University College of London, Department of Medicine, Rayne Building, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rauramaa+R%22">Rauramaa R</searchLink>; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22de+Faire+U%22">de Faire U</searchLink>; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, and Department of Cardiology, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Smit+AJ%22">Smit AJ</searchLink>; Department of Medicine, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Giral+P%22">Giral P</searchLink>; Assistance Publique - Hopitaux de Paris; Service Endocrinologie-Metabolisme, Groupe Hôpitalier Pitie-Salpetriere, Unités de Prévention Cardiovasculaire, Paris, France.<br /><searchLink fieldCode="AU" term="%22Kurl+S%22">Kurl S</searchLink>; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Mannarino+E%22">Mannarino E</searchLink>; Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Enroth+S%22">Enroth S</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Johansson+Å%22">Johansson Å</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Enroth+SB%22">Enroth SB</searchLink>; Department of Internal Medicine, Uppsala University Hospital, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Gustafsson+S%22">Gustafsson S</searchLink>; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Lind+L%22">Lind L</searchLink>; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Lindgren+C%22">Lindgren C</searchLink>; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Morris+AP%22">Morris AP</searchLink>; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Giedraitis+V%22">Giedraitis V</searchLink>; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Silveira+A%22">Silveira A</searchLink>; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Franco-Cereceda+A%22">Franco-Cereceda A</searchLink>; Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Tremoli+E%22">Tremoli E</searchLink>; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gyllensten+U%22">Gyllensten U</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Ingelsson+E%22">Ingelsson E</searchLink>; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Brunak+S%22">Brunak S</searchLink>; Department of Systems Biology, Technical University of Denmark, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Eriksson+P%22">Eriksson P</searchLink>; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Ziemek+D%22">Ziemek D</searchLink>; Pfizer Worldwide Research & Development, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Hamsten+A%22">Hamsten A</searchLink>; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Mälarstig+A%22">Mälarstig A</searchLink>; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Pfizer Worldwide Research and Development, Stockholm, Sweden.
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