Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models.

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Title: Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models.
Authors: Megaw R; MRC Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK. roly.megaw@ed.ac.uk., Abu-Arafeh H; MRC Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK., Jungnickel M; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK., Mellough C; Institute of Genetic Medicine, Newcastle University, Newcastle, NE1 3BZ, UK., Gurniak C; Institute fur Genetik, Universitat Bonn, Karlrobert-Kreiten-Strasse. 13, 53115, Bonn, Germany., Witke W; Institute fur Genetik, Universitat Bonn, Karlrobert-Kreiten-Strasse. 13, 53115, Bonn, Germany., Zhang W; Department of Ophthalmology, UMASS Medical School, 368 Plantation St, Albert Sherman Center, AS6-2043, Worcester, Massachusetts, 01605, USA., Khanna H; Department of Ophthalmology, UMASS Medical School, 368 Plantation St, Albert Sherman Center, AS6-2043, Worcester, Massachusetts, 01605, USA., Mill P; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK., Dhillon B; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Wright AF; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK., Lako M; Institute of Genetic Medicine, Newcastle University, Newcastle, NE1 3BZ, UK., Ffrench-Constant C; MRC Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK.
Source: Nature communications [Nat Commun] 2017 Aug 16; Vol. 8 (1), pp. 271. Date of Electronic Publication: 2017 Aug 16.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-017-00111-8