TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter.

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Title: TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter.
Authors: Rajagopalan D; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Pandey AK; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Xiuzhen MC; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Lee KK; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Hora S; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Zhang Y; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Chua BH; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Kwok HS; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Bhatia SS; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Deng LW; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Tenen DG; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA, United States of America., Kappei D; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Jha S; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Source: PLoS pathogens [PLoS Pathog] 2017 Oct 18; Vol. 13 (10), pp. e1006681. Date of Electronic Publication: 2017 Oct 18 (Print Publication: 2017).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1553-7374
DOI:10.1371/journal.ppat.1006681