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Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice.

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Title: Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice.
Authors: Winn SR; Department of Medical and Molecular Genetics, Oregon Health & Science University, Mailstop L-103, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA., Scherer T; Department of Pediatrics, University of Zurich, Steinweissstrasse 75, Zurich CH-8032, Switzerland., Thöny B; Department of Pediatrics, University of Zurich, Steinweissstrasse 75, Zurich CH-8032, Switzerland., Ying M; Department of Biomedicine, KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, 5009 Bergen, Norway., Martinez A; Department of Biomedicine, KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, 5009 Bergen, Norway., Weber S; Department of Behavioral Neuroscience, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA., Raber J; Department of Behavioral Neuroscience, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA; Department of Neurology, Division of Neuroscience, ONPRC, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA; Department of Radiation Medicine, Division of Neuroscience, ONPRC, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA., Harding CO; Department of Medical and Molecular Genetics, Oregon Health & Science University, Mailstop L-103, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA. Electronic address: hardingc@ohsu.edu.
Source: Molecular genetics and metabolism [Mol Genet Metab] 2018 Jan; Vol. 123 (1), pp. 6-20. Date of Electronic Publication: 2017 Oct 19.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9805456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-7206 (Electronic) Linking ISSN: 10967192 NLM ISO Abbreviation: Mol Genet Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice.
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  Data: <searchLink fieldCode="AU" term="%22Winn+SR%22">Winn SR</searchLink>; Department of Medical and Molecular Genetics, Oregon Health & Science University, Mailstop L-103, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA.<br /><searchLink fieldCode="AU" term="%22Scherer+T%22">Scherer T</searchLink>; Department of Pediatrics, University of Zurich, Steinweissstrasse 75, Zurich CH-8032, Switzerland.<br /><searchLink fieldCode="AU" term="%22Thöny+B%22">Thöny B</searchLink>; Department of Pediatrics, University of Zurich, Steinweissstrasse 75, Zurich CH-8032, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ying+M%22">Ying M</searchLink>; Department of Biomedicine, KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, 5009 Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Martinez+A%22">Martinez A</searchLink>; Department of Biomedicine, KG Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, 5009 Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Weber+S%22">Weber S</searchLink>; Department of Behavioral Neuroscience, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA.<br /><searchLink fieldCode="AU" term="%22Raber+J%22">Raber J</searchLink>; Department of Behavioral Neuroscience, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA; Department of Neurology, Division of Neuroscience, ONPRC, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA; Department of Radiation Medicine, Division of Neuroscience, ONPRC, Oregon Health & Science University, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA.<br /><searchLink fieldCode="AU" term="%22Harding+CO%22">Harding CO</searchLink>; Department of Medical and Molecular Genetics, Oregon Health & Science University, Mailstop L-103, 3181 Sam Jackson Park Rd., Portland, OR 97239, USA. Electronic address: hardingc@ohsu.edu.
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  Data: <searchLink fieldCode="JN" term="%229805456%22">Molecular genetics and metabolism</searchLink> [Mol Genet Metab] 2018 Jan; Vol. 123 (1), pp. 6-20. <i>Date of Electronic Publication: </i>2017 Oct 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9805456 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-7206 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210967192%22">10967192 </searchLink><i>NLM ISO Abbreviation: </i>Mol Genet Metab <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.ymgme.2017.10.009
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        Text: English
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              Text: 2018 Jan
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