Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles.

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Title: Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles.
Authors: Zhang N; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Zoltner M; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Leung KF; Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Scullion P; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Hutchinson S; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Del Pino RC; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Vincent IM; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom., Zhang YK; Anacor Pharmaceuticals, Inc., Palo Alto, California, United States of America., Freund YR; Anacor Pharmaceuticals, Inc., Palo Alto, California, United States of America., Alley MRK; Anacor Pharmaceuticals, Inc., Palo Alto, California, United States of America., Jacobs RT; Anacor Pharmaceuticals, Inc., Palo Alto, California, United States of America., Read KD; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Barrett MP; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom., Horn D; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Field MC; Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Source: PLoS pathogens [PLoS Pathog] 2018 Feb 09; Vol. 14 (2), pp. e1006850. Date of Electronic Publication: 2018 Feb 09 (Print Publication: 2018).
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1553-7374
DOI:10.1371/journal.ppat.1006850