Tetrahydrobiopterin treatment reduces brain L-Phe but only partially improves serotonin in hyperphenylalaninemic ENU1/2 mice.
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| Title: | Tetrahydrobiopterin treatment reduces brain L-Phe but only partially improves serotonin in hyperphenylalaninemic ENU1/2 mice. |
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| Authors: | Scherer T; Department of Pediatrics, Divisions of Metabolism and of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland., Allegri G; Department of Pediatrics, Divisions of Metabolism and of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland., Sarkissian CN; Department of Biology, McGill University, Montreal, QC, H3A 1B1, Canada., Ying M; Department of Biomedicine and K.G. Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Bergen, Norway., Grisch-Chan HM; Department of Pediatrics, Divisions of Metabolism and of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland., Rassi A; Department of Pediatrics, Divisions of Metabolism and of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland., Winn SR; Department of Molecular and Medical Genetics, School of Medicine, Oregon Science & Health University, Portland, OR, USA., Harding CO; Department of Molecular and Medical Genetics, School of Medicine, Oregon Science & Health University, Portland, OR, USA., Martinez A; Department of Biomedicine and K.G. Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Bergen, Norway. aurora.martinez@uib.no., Thöny B; Department of Pediatrics, Divisions of Metabolism and of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland. beat.thony@kispi.uzh.ch. |
| Source: | Journal of inherited metabolic disease [J Inherit Metab Dis] 2018 Jul; Vol. 41 (4), pp. 709-718. Date of Electronic Publication: 2018 Mar 08. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 7910918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2665 (Electronic) Linking ISSN: 01418955 NLM ISO Abbreviation: J Inherit Metab Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1573-2665 |
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| DOI: | 10.1007/s10545-018-0150-y |
