Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer.
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| Title: | Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer. |
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| Authors: | Tanyi JL; Ovarian Cancer Research Center, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Bobisse S; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland., Ophir E; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland., Tuyaerts S; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland., Roberti A; Ovarian Cancer Research Center, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Genolet R; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland., Baumgartner P; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland., Stevenson BJ; Swiss Institute of Bioinformatics, Lausanne CH-1015, Switzerland., Iseli C; Swiss Institute of Bioinformatics, Lausanne CH-1015, Switzerland., Dangaj D; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland., Czerniecki B; Department of Breast Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA., Semilietof A; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland., Racle J; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland.; Swiss Institute of Bioinformatics, Lausanne CH-1015, Switzerland., Michel A; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland., Xenarios I; Swiss Institute of Bioinformatics, Lausanne CH-1015, Switzerland., Chiang C; Ovarian Cancer Research Center, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Monos DS; Immunogenetics Laboratory, Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Torigian DA; Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA., Nisenbaum HL; Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA., Michielin O; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland.; Swiss Institute of Bioinformatics, Lausanne CH-1015, Switzerland., June CH; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA 19104, USA., Levine BL; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA 19104, USA., Powell DJ Jr; Ovarian Cancer Research Center, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Gfeller D; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland.; Swiss Institute of Bioinformatics, Lausanne CH-1015, Switzerland., Mick R; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Dafni U; Laboratory of Biostatistics, School of Health Sciences, National and Kapodistrian, University of Athens, Athens, Greece., Zoete V; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland.; Swiss Institute of Bioinformatics, Lausanne CH-1015, Switzerland., Harari A; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland., Coukos G; Ovarian Cancer Research Center, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland., Kandalaft LE; Ovarian Cancer Research Center, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. lana.kandalaft@chuv.ch.; Department of Oncology, Lausanne University Hospital, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne CH-1066, Switzerland. |
| Source: | Science translational medicine [Sci Transl Med] 2018 Apr 11; Vol. 10 (436). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.aao5931 |
