Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.

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Title: Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Authors: Gagnon SML; Department of Biochemistry & Microbiology, University of Victoria, STN CSC, Victoria, BC, Canada., Legg MSG; Department of Biochemistry & Microbiology, University of Victoria, STN CSC, Victoria, BC, Canada., Polakowski R; Department of Chemistry, University of Alberta, Edmonton, AB, Canada., Letts JA; Department of Biochemistry & Microbiology, University of Victoria, STN CSC, Victoria, BC, Canada., Persson M; Carlsberg Laboratory, Gamle Carlsberg Vej 4-10, Copenhagen V, Denmark., Lin S; Department of Chemistry, University of Alberta, Edmonton, AB, Canada., Zheng RB; Department of Chemistry, University of Alberta, Edmonton, AB, Canada., Rempel B; Department of Chemistry, University of Alberta, Edmonton, AB, Canada., Schuman B; Department of Biochemistry & Microbiology, University of Victoria, STN CSC, Victoria, BC, Canada., Haji-Ghassemi O; Department of Biochemistry & Microbiology, University of Victoria, STN CSC, Victoria, BC, Canada., Borisova SN; Department of Biochemistry & Microbiology, University of Victoria, STN CSC, Victoria, BC, Canada., Palcic MM; Department of Biochemistry & Microbiology, University of Victoria, STN CSC, Victoria, BC, Canada.; Department of Chemistry, University of Alberta, Edmonton, AB, Canada.; Carlsberg Laboratory, Gamle Carlsberg Vej 4-10, Copenhagen V, Denmark., Evans SV; Department of Biochemistry & Microbiology, University of Victoria, STN CSC, Victoria, BC, Canada.
Source: Glycobiology [Glycobiology] 2018 Aug 01; Vol. 28 (8), pp. 624-636.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9104124 Publication Model: Print Cited Medium: Internet ISSN: 1460-2423 (Electronic) Linking ISSN: 09596658 NLM ISO Abbreviation: Glycobiology Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1460-2423
DOI:10.1093/glycob/cwy051