Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: a randomized controlled trial.

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Title: Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: a randomized controlled trial.
Authors: Syn NL; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Wong AL; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lee SC; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Teoh HL; Division of Neurology, Department of Medicine, National University Health System, Singapore, Singapore., Yip JWL; Department of Cardiology, National University Heart Centre, Singapore, Singapore., Seet RC; Division of Neurology, Department of Medicine, National University Health System, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Yeo WT; Department of Cardiology, National University Heart Centre, Singapore, Singapore., Kristanto W; Department of Cardiology, National University Heart Centre, Singapore, Singapore., Bee PC; Department of Medicine, University of Malaya Medical Centre, Kuala Lumpur, Malaysia., Poon LM; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore., Marban P; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore., Wu TS; Department of Pharmacy, National University Hospital, Singapore, Singapore., Winther MD; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Brunham LR; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Medicine, Centre for Heart Lung Innovation, University of British Columbia, Vancouver, Canada., Soong R; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore., Tai BC; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Goh BC; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore. phcgbc@nus.edu.sg.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. phcgbc@nus.edu.sg.; Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore, 119228, Singapore. phcgbc@nus.edu.sg.
Source: BMC medicine [BMC Med] 2018 Jul 10; Vol. 16 (1), pp. 104. Date of Electronic Publication: 2018 Jul 10.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1741-7015
DOI:10.1186/s12916-018-1093-8