Prophylactic Treatment With Simvastatin Modulates the Immune Response and Increases Animal Survival Following Lethal Sepsis Infection.

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Title: Prophylactic Treatment With Simvastatin Modulates the Immune Response and Increases Animal Survival Following Lethal Sepsis Infection.
Authors: Braga Filho JAF; Laboratory of Immunophysiology, Federal University of Maranhão, São Luís, Brazil., Abreu AG; Programa de Pós-Graduação em Ciências da Saúde, Federal University of Maranhão, São Luís, Brazil.; CEUMA University, São Luís, Brazil., Rios CEP; Laboratory of Immunophysiology, Federal University of Maranhão, São Luís, Brazil., Trovão LO; Laboratory of Immunophysiology, Federal University of Maranhão, São Luís, Brazil., Silva DLF; Laboratory of Immunophysiology, Federal University of Maranhão, São Luís, Brazil., Cysne DN; Laboratory of Immunophysiology, Federal University of Maranhão, São Luís, Brazil., Nascimento JR; Laboratory of Immunophysiology, Federal University of Maranhão, São Luís, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Federal University of Maranhão, São Luís, Brazil., Fortes TS; Laboratory of Immunophysiology, Federal University of Maranhão, São Luís, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Federal University of Maranhão, São Luís, Brazil., Silva LA; Laboratory of Immunophysiology, Federal University of Maranhão, São Luís, Brazil., Guerra RNM; Laboratory of Immunophysiology, Federal University of Maranhão, São Luís, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Federal University of Maranhão, São Luís, Brazil., Maciel MCG; Programa de Pós-Graduação em Ciências da Saúde, Federal University of Maranhão, São Luís, Brazil., Serezani CH; Division of Infectious Diseases, Departments of Medicine, Pathology, Microbiology and Immunology, Institute for Infection, Immunology and Inflammation, Vanderbilt University School of Medicine, Nashville, TN, United States., Nascimento FRF; Laboratory of Immunophysiology, Federal University of Maranhão, São Luís, Brazil.; Programa de Pós-Graduação em Ciências da Saúde, Federal University of Maranhão, São Luís, Brazil.
Source: Frontiers in immunology [Front Immunol] 2018 Sep 21; Vol. 9, pp. 2137. Date of Electronic Publication: 2018 Sep 21 (Print Publication: 2018).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1664-3224
DOI:10.3389/fimmu.2018.02137