shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth.
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| Title: | shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth. |
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| Authors: | Haynes HR; Brain Tumour Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Department of Cellular Pathology, North Bristol NHS Trust, Bristol, UK., Scott HL; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Killick-Cole CL; Functional Neurosurgery Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Shaw G; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Brend T; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Hares KM; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Redondo J; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Kemp KC; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Ballesteros LS; Flow Cytometry Facility, School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Herman A; Flow Cytometry Facility, School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Cordero-Llana O; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Singleton WG; Functional Neurosurgery Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Department of Neurosurgery, North Bristol NHS Trust, Bristol, UK., Mills F; Department of Clinical Biochemistry, North Bristol NHS Trust, Bristol, UK., Batstone T; Bioinformatics Facility, School of Biological Sciences, University of Bristol, Bristol, UK., Bulstrode H; Department of Clinical Neuroscience and Stem Cell Institute, University of Cambridge, Cambridge, UK., Kauppinen RA; Clinical Research and Imaging Centre, University of Bristol, Bristol, UK., Wurdak H; Stem Cells and Brain Tumour Group, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Uney JB; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Short SC; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Wilkins A; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Kurian KM; Brain Tumour Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. |
| Source: | The Journal of pathology [J Pathol] 2019 Apr; Vol. 247 (4), pp. 422-434. Date of Electronic Publication: 2018 Dec 27. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1096-9896 |
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| DOI: | 10.1002/path.5201 |
