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shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth.

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Title: shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth.
Authors: Haynes HR; Brain Tumour Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Department of Cellular Pathology, North Bristol NHS Trust, Bristol, UK., Scott HL; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Killick-Cole CL; Functional Neurosurgery Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Shaw G; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Brend T; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Hares KM; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Redondo J; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Kemp KC; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Ballesteros LS; Flow Cytometry Facility, School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Herman A; Flow Cytometry Facility, School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Cordero-Llana O; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Singleton WG; Functional Neurosurgery Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Department of Neurosurgery, North Bristol NHS Trust, Bristol, UK., Mills F; Department of Clinical Biochemistry, North Bristol NHS Trust, Bristol, UK., Batstone T; Bioinformatics Facility, School of Biological Sciences, University of Bristol, Bristol, UK., Bulstrode H; Department of Clinical Neuroscience and Stem Cell Institute, University of Cambridge, Cambridge, UK., Kauppinen RA; Clinical Research and Imaging Centre, University of Bristol, Bristol, UK., Wurdak H; Stem Cells and Brain Tumour Group, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Uney JB; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Short SC; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Wilkins A; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Kurian KM; Brain Tumour Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Source: The Journal of pathology [J Pathol] 2019 Apr; Vol. 247 (4), pp. 422-434. Date of Electronic Publication: 2018 Dec 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth.
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  Data: <searchLink fieldCode="AU" term="%22Haynes+HR%22">Haynes HR</searchLink>; Brain Tumour Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Department of Cellular Pathology, North Bristol NHS Trust, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Scott+HL%22">Scott HL</searchLink>; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Killick-Cole+CL%22">Killick-Cole CL</searchLink>; Functional Neurosurgery Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Shaw+G%22">Shaw G</searchLink>; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Brend+T%22">Brend T</searchLink>; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Hares+KM%22">Hares KM</searchLink>; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Redondo+J%22">Redondo J</searchLink>; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Kemp+KC%22">Kemp KC</searchLink>; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Ballesteros+LS%22">Ballesteros LS</searchLink>; Flow Cytometry Facility, School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Herman+A%22">Herman A</searchLink>; Flow Cytometry Facility, School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Cordero-Llana+O%22">Cordero-Llana O</searchLink>; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Singleton+WG%22">Singleton WG</searchLink>; Functional Neurosurgery Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Department of Neurosurgery, North Bristol NHS Trust, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Mills+F%22">Mills F</searchLink>; Department of Clinical Biochemistry, North Bristol NHS Trust, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Batstone+T%22">Batstone T</searchLink>; Bioinformatics Facility, School of Biological Sciences, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Bulstrode+H%22">Bulstrode H</searchLink>; Department of Clinical Neuroscience and Stem Cell Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kauppinen+RA%22">Kauppinen RA</searchLink>; Clinical Research and Imaging Centre, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Wurdak+H%22">Wurdak H</searchLink>; Stem Cells and Brain Tumour Group, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Uney+JB%22">Uney JB</searchLink>; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Short+SC%22">Short SC</searchLink>; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Wilkins+A%22">Wilkins A</searchLink>; Multiple Sclerosis and Stem Cell Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Kurian+KM%22">Kurian KM</searchLink>; Brain Tumour Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
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  Data: <searchLink fieldCode="JN" term="%220204634%22">The Journal of pathology</searchLink> [J Pathol] 2019 Apr; Vol. 247 (4), pp. 422-434. <i>Date of Electronic Publication: </i>2018 Dec 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+And+Sons%22">John Wiley And Sons </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0204634 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-9896 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223417%22">00223417 </searchLink><i>NLM ISO Abbreviation: </i>J Pathol <i>Subsets: </i>MEDLINE
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