Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.

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Bibliographic Details
Title: Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.
Authors: Jacobs RT; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Lunde CS; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Freund YR; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Hernandez V; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Li X; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Xia Y; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Carter DS; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Berry PW; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Halladay J; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Rock F; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Stefanakis R; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Easom E; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Plattner JJ; Anacor Pharmaceuticals , 1020 East Meadow Circle , Palo Alto , California 94303 , United States., Ford L; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Johnston KL; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Cook DAN; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Clare R; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Cassidy A; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Myhill L; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Tyrer H; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Gamble J; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Guimaraes AF; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Steven A; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Lenz F; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany., Ehrens A; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany., Frohberger SJ; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany., Koschel M; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany., Hoerauf A; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany., Hübner MP; Institute for Medical Microbiology, Immunology and Parasitology , University Hospital Bonn , Sigmund Freud Str. 25 , 53127 Bonn , Germany., McNamara CW; Calibr , 11119 North Torrey Pines Road , Suite 100, La Jolla , California 92037 , United States., Bakowski MA; Calibr , 11119 North Torrey Pines Road , Suite 100, La Jolla , California 92037 , United States., Turner JD; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Taylor MJ; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K., Ward SA; Centre for Drugs and Diagnostics, Department of Parasitology , Liverpool School of Tropical Medicine , Pembroke Place , Liverpool L3 5QA , U.K.
Source: Journal of medicinal chemistry [J Med Chem] 2019 Mar 14; Vol. 62 (5), pp. 2521-2540. Date of Electronic Publication: 2019 Feb 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-4804
DOI:10.1021/acs.jmedchem.8b01854