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Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.

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Title: Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.
Authors: Sasako T; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan.; Translational Systems Biology and Medicine Initiative (TSBMI), The University of Tokyo, Tokyo, 113-8655, Japan.; Department of Molecular Diabetic Medicine, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan.; Division for Health Service Promotion, The University of Tokyo, Tokyo, 113-0033, Japan.; Department of Molecular Sciences on Diabetes, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan., Ohsugi M; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan., Kubota N; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan.; Translational Systems Biology and Medicine Initiative (TSBMI), The University of Tokyo, Tokyo, 113-8655, Japan.; Department of Clinical Nutrition Therapy, The University of Tokyo Hospital, The University of Tokyo, Tokyo, 113-865, Japan., Itoh S; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan.; Kowa Company Limited, Nagoya, 460-0003, Japan., Okazaki Y; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan.; Department of Molecular Diabetic Medicine, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan., Terai A; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan.; Department of Molecular Diabetic Medicine, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan., Kubota T; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan.; Clinical Nutrition Program, National Institute of Health and Nutrition, Tokyo, 162-8636, Japan.; Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo, 143-8541, Japan., Yamashita S; Department of Systems BioMedicine, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan., Nakatsukasa K; Division of Biological Sciences, Graduate School of Science, Nagoya University, Nagoya, 464-8601, Japan.; Graduate School of Natural Sciences, Nagoya City University, Nagoya, 464-8601, Japan., Kamura T; Division of Biological Sciences, Graduate School of Science, Nagoya University, Nagoya, 464-8601, Japan., Iwayama K; Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba, 305-8577, Japan., Tokuyama K; Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba, 305-8577, Japan., Kiyonari H; Animal Resource Development Unit, RIKEN Center for Life Science Technologies, Kobe, 650-0047, Japan.; Genetic Engineering Team, RIKEN Center for Life Science Technologies, Kobe, 650-0047, Japan., Furuta Y; Animal Resource Development Unit, RIKEN Center for Life Science Technologies, Kobe, 650-0047, Japan.; Genetic Engineering Team, RIKEN Center for Life Science Technologies, Kobe, 650-0047, Japan., Shibahara J; Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan., Fukayama M; Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan., Enooku K; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan., Okushin K; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan., Tsutsumi T; Department of Infectious Disease, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan., Tateishi R; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan., Tobe K; The First Department of Internal Medicine, Graduate School of Medicine and Pharmaceutical Sciences of Research, The University of Toyama, Toyama, 930-8555, Japan., Asahara H; Department of Systems BioMedicine, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan., Koike K; Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan., Kadowaki T; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan. kadowaki-3im@h.u-tokyo.ac.jp.; Translational Systems Biology and Medicine Initiative (TSBMI), The University of Tokyo, Tokyo, 113-8655, Japan. kadowaki-3im@h.u-tokyo.ac.jp.; Department of Prevention of Diabetes and Lifestyle-Related Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan. kadowaki-3im@h.u-tokyo.ac.jp.; Department of Metabolism and Nutrition, Mizonokuchi Hospital, Faculty of Medicine, Teikyo University, Tokyo, 213-8507, Japan. kadowaki-3im@h.u-tokyo.ac.jp., Ueki K; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-8655, Japan. ueki-tky@umin.net.; Translational Systems Biology and Medicine Initiative (TSBMI), The University of Tokyo, Tokyo, 113-8655, Japan. ueki-tky@umin.net.; Department of Molecular Diabetic Medicine, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan. ueki-tky@umin.net.
Source: Nature communications [Nat Commun] 2019 Feb 27; Vol. 10 (1), pp. 947. Date of Electronic Publication: 2019 Feb 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-019-08591-6