Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation.

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Title: Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation.
Authors: Tsytlonok M; VIB Center for Structural Biology, Vrije Universiteit Brussel, Pleinlaan, 2 1050, Brussels, Belgium., Sanabria H; Department of Physics and Astronomy, Clemson University, Clemson, SC, 29634, USA.; Lehrstuhl für Molekulare Physikalische Chemie, Heinrich-Heine-Universität, 40225, Düsseldorf, Germany., Wang Y; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.; Department of Radiation Oncology, West Cancer Center and Research Institute, Memphis, TN, 38138, USA., Felekyan S; Lehrstuhl für Molekulare Physikalische Chemie, Heinrich-Heine-Universität, 40225, Düsseldorf, Germany., Hemmen K; Lehrstuhl für Molekulare Physikalische Chemie, Heinrich-Heine-Universität, 40225, Düsseldorf, Germany., Phillips AH; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA., Yun MK; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA., Waddell MB; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.; Molecular Interaction Analysis Shared Resource, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38103, USA., Park CG; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA., Vaithiyalingam S; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.; Molecular Interaction Analysis Shared Resource, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38103, USA., Iconaru L; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA., White SW; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA., Tompa P; VIB Center for Structural Biology, Vrije Universiteit Brussel, Pleinlaan, 2 1050, Brussels, Belgium. tompa@enzim.hu.; Institute of Enzymology, Research Centre for Natural Sciences of the Hungarian Academy of Sciences, Budapest, Hungary. tompa@enzim.hu., Seidel CAM; Lehrstuhl für Molekulare Physikalische Chemie, Heinrich-Heine-Universität, 40225, Düsseldorf, Germany. cseidel@hhu.de., Kriwacki R; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. richard.kriwacki@stjude.org.; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Sciences Center, Memphis, TN, 38163, USA. richard.kriwacki@stjude.org.
Source: Nature communications [Nat Commun] 2019 Apr 11; Vol. 10 (1), pp. 1676. Date of Electronic Publication: 2019 Apr 11.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-019-09446-w