Population pharmacokinetics and pharmacodynamics of the artesunate-mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children.

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Title: Population pharmacokinetics and pharmacodynamics of the artesunate-mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children.
Authors: Guidi M; School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland.; Laboratory and Service of Clinical Pharmacology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland., Mercier T; Laboratory and Service of Clinical Pharmacology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland., Aouri M; Laboratory and Service of Clinical Pharmacology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland., Decosterd LA; Laboratory and Service of Clinical Pharmacology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland., Csajka C; School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland.; Laboratory and Service of Clinical Pharmacology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland., Ogutu B; Kenya Medical Research Institute, Kisumu, Kenya., Carn G; Drugs for Neglected Diseases initiative, Geneva, Switzerland., Kiechel JR; Drugs for Neglected Diseases initiative, Geneva, Switzerland. jean-rene.kiechel@wanadoo.fr.
Source: Malaria journal [Malar J] 2019 Apr 18; Vol. 18 (1), pp. 139. Date of Electronic Publication: 2019 Apr 18.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1475-2875
DOI:10.1186/s12936-019-2754-6