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Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel.

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Title: Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel.
Authors: O'Reilly M, Kirkwood NK, Kenyon EJ, Huckvale R, Cantillon DM; Wellcome Trust Centre for Global Health Research, Brighton and Sussex Medical School , University of Sussex , Falmer , Brighton BN1 9PX , U.K., Waddell SJ; Wellcome Trust Centre for Global Health Research, Brighton and Sussex Medical School , University of Sussex , Falmer , Brighton BN1 9PX , U.K., Ward SE; Medicines Discovery Institute , Cardiff University , Park Place , Cardiff CF10 3AT , U.K., Richardson GP, Kros CJ, Derudas M
Source: Journal of medicinal chemistry [J Med Chem] 2019 Jun 13; Vol. 62 (11), pp. 5312-5329. Date of Electronic Publication: 2019 May 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel.
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2019 Jun 13; Vol. 62 (11), pp. 5312-5329. <i>Date of Electronic Publication: </i>2019 May 24.
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        Value: 10.1021/acs.jmedchem.8b01325
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      – TitleFull: Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel.
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              Text: 2019 Jun 13
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