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Mitochondrial complex I inhibitor deguelin induces metabolic reprogramming and sensitizes vemurafenib-resistant BRAFV600E mutation bearing metastatic melanoma cells.

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Title: Mitochondrial complex I inhibitor deguelin induces metabolic reprogramming and sensitizes vemurafenib-resistant BRAFV600E mutation bearing metastatic melanoma cells.
Authors: Carpenter EL; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.; Department of Dermatology, Oregon Health & Science University, Portland, Oregon., Chagani S; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon., Nelson D; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon., Cassidy PB; Department of Dermatology, Oregon Health & Science University, Portland, Oregon.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon., Laws M; Department of Dermatology, Oregon Health & Science University, Portland, Oregon., Ganguli-Indra G; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon., Indra AK; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.; Department of Dermatology, Oregon Health & Science University, Portland, Oregon.; Department of Biochemistry and Biophysics, OSU, Corvallis, Oregon.; Linus Pauling Institute, Oregon State University, Corvallis, Oregon.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon.
Source: Molecular carcinogenesis [Mol Carcinog] 2019 Sep; Vol. 58 (9), pp. 1680-1690. Date of Electronic Publication: 2019 Jun 18.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8811105 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2744 (Electronic) Linking ISSN: 08991987 NLM ISO Abbreviation: Mol Carcinog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mitochondrial complex I inhibitor deguelin induces metabolic reprogramming and sensitizes vemurafenib-resistant BRAF<superscript>V600E</superscript> mutation bearing metastatic melanoma cells.
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  Data: <searchLink fieldCode="AU" term="%22Carpenter+EL%22">Carpenter EL</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.; Department of Dermatology, Oregon Health & Science University, Portland, Oregon.<br /><searchLink fieldCode="AU" term="%22Chagani+S%22">Chagani S</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.<br /><searchLink fieldCode="AU" term="%22Nelson+D%22">Nelson D</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.<br /><searchLink fieldCode="AU" term="%22Cassidy+PB%22">Cassidy PB</searchLink>; Department of Dermatology, Oregon Health & Science University, Portland, Oregon.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon.<br /><searchLink fieldCode="AU" term="%22Laws+M%22">Laws M</searchLink>; Department of Dermatology, Oregon Health & Science University, Portland, Oregon.<br /><searchLink fieldCode="AU" term="%22Ganguli-Indra+G%22">Ganguli-Indra G</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon.<br /><searchLink fieldCode="AU" term="%22Indra+AK%22">Indra AK</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon.; Department of Dermatology, Oregon Health & Science University, Portland, Oregon.; Department of Biochemistry and Biophysics, OSU, Corvallis, Oregon.; Linus Pauling Institute, Oregon State University, Corvallis, Oregon.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon.
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  Data: <searchLink fieldCode="JN" term="%228811105%22">Molecular carcinogenesis</searchLink> [Mol Carcinog] 2019 Sep; Vol. 58 (9), pp. 1680-1690. <i>Date of Electronic Publication: </i>2019 Jun 18.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Liss%22">Wiley-Liss </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8811105 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-2744 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208991987%22">08991987 </searchLink><i>NLM ISO Abbreviation: </i>Mol Carcinog <i>Subsets: </i>MEDLINE
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        Value: 10.1002/mc.23068
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        Text: English
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      – TitleFull: Mitochondrial complex I inhibitor deguelin induces metabolic reprogramming and sensitizes vemurafenib-resistant BRAFV600E mutation bearing metastatic melanoma cells.
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              Text: 2019 Sep
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