Development and validation of a chiral LC-ESI-MS/MS method for simultaneous determination of the enantiomeric metabolites isosorbide 2-mononitrate and isosorbide 5-mononitrate of isosorbide dinitrate in rat and human plasma.
Saved in:
| Title: | Development and validation of a chiral LC-ESI-MS/MS method for simultaneous determination of the enantiomeric metabolites isosorbide 2-mononitrate and isosorbide 5-mononitrate of isosorbide dinitrate in rat and human plasma. |
|---|---|
| Authors: | Patel BD; Department of Drug Metabolism Pharmacokinetics and Bioanalysis, Eurofins Advinus Ltd., 21 & 22, Phase II, Peenya Industrial Area, Bengaluru, 560058, India; Department of Chemistry, PAHER University, Udaipur, Rajasthan, India. Electronic address: BhaveshPatel3@eurofins.com., Pulakundam N; Department of Drug Metabolism Pharmacokinetics and Bioanalysis, Eurofins Advinus Ltd., 21 & 22, Phase II, Peenya Industrial Area, Bengaluru, 560058, India., Gadekar AR; Department of Drug Metabolism Pharmacokinetics and Bioanalysis, Eurofins Advinus Ltd., 21 & 22, Phase II, Peenya Industrial Area, Bengaluru, 560058, India., Raje AA; Department of Drug Metabolism Pharmacokinetics and Bioanalysis, Eurofins Advinus Ltd., 21 & 22, Phase II, Peenya Industrial Area, Bengaluru, 560058, India., Ramanathan V; Department of Drug Metabolism Pharmacokinetics and Bioanalysis, Eurofins Advinus Ltd., 21 & 22, Phase II, Peenya Industrial Area, Bengaluru, 560058, India., Ameta R; Department of Chemistry, PAHER University, Udaipur, Rajasthan, India. |
| Source: | Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2019 Sep 10; Vol. 174, pp. 396-405. Date of Electronic Publication: 2019 Jun 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
