Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.
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| Title: | Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye. |
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| Authors: | Shatz W; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Hass PE; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Peer N; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Paluch MT; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Blanchette C; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Han G; Microchemistry, Proteomics and Lipidomics, Genentech Inc., South San Francisco, California, United States of America., Sandoval W; Microchemistry, Proteomics and Lipidomics, Genentech Inc., South San Francisco, California, United States of America., Morando A; Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, California, United States of America., Loyet KM; Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, California, United States of America., Bantseev V; Safety Assessment, Genentech Inc., South San Francisco, California, United States of America., Booler H; Safety Assessment, Genentech Inc., South San Francisco, California, United States of America., Crowell S; Pre-clinical and Translational Pharmacokinetics, Genentech Inc., South San Francisco, California, United States of America., Kamath A; Pre-clinical and Translational Pharmacokinetics, Genentech Inc., South San Francisco, California, United States of America., Scheer JM; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Kelley RF; Drug Delivery, Genentech, South San Francisco, California, United States of America. |
| Source: | PloS one [PLoS One] 2019 Jun 28; Vol. 14 (6), pp. e0218613. Date of Electronic Publication: 2019 Jun 28 (Print Publication: 2019). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0218613 |
