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Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.

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Title: Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.
Authors: Shatz W; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Hass PE; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Peer N; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Paluch MT; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Blanchette C; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Han G; Microchemistry, Proteomics and Lipidomics, Genentech Inc., South San Francisco, California, United States of America., Sandoval W; Microchemistry, Proteomics and Lipidomics, Genentech Inc., South San Francisco, California, United States of America., Morando A; Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, California, United States of America., Loyet KM; Biochemical and Cellular Pharmacology, Genentech Inc., South San Francisco, California, United States of America., Bantseev V; Safety Assessment, Genentech Inc., South San Francisco, California, United States of America., Booler H; Safety Assessment, Genentech Inc., South San Francisco, California, United States of America., Crowell S; Pre-clinical and Translational Pharmacokinetics, Genentech Inc., South San Francisco, California, United States of America., Kamath A; Pre-clinical and Translational Pharmacokinetics, Genentech Inc., South San Francisco, California, United States of America., Scheer JM; Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America., Kelley RF; Drug Delivery, Genentech, South San Francisco, California, United States of America.
Source: PloS one [PLoS One] 2019 Jun 28; Vol. 14 (6), pp. e0218613. Date of Electronic Publication: 2019 Jun 28 (Print Publication: 2019).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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