Assessment of the effect of erdafitinib on cardiac safety: analysis of ECGs and exposure-QTc in patients with advanced or refractory solid tumors.

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Title: Assessment of the effect of erdafitinib on cardiac safety: analysis of ECGs and exposure-QTc in patients with advanced or refractory solid tumors.
Authors: Valade E; Janssen Research and Development, Turnhoutseweg 30, 2340, Beerse, Antwerp, Belgium., Dosne AG; Janssen Research and Development, Turnhoutseweg 30, 2340, Beerse, Antwerp, Belgium. adosne@its.jnj.com., Xie H; Janssen Research and Development, Spring House, PA, USA., Kleiman R; eResearch Technology Inc. (ERT), Philadelphia, PA, USA., Li LY; Janssen Research and Development, Spring House, PA, USA., Perez-Ruixo JJ; Janssen Research and Development, Turnhoutseweg 30, 2340, Beerse, Antwerp, Belgium., Ouellet D; Janssen Research and Development, Spring House, PA, USA.
Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2019 Sep; Vol. 84 (3), pp. 621-633. Date of Electronic Publication: 2019 Jul 06.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0843
DOI:10.1007/s00280-019-03896-1