Hepatocyte spheroids as a viable in vitro model for recapitulation of complex in vivo metabolism pathways of loratadine in humans.
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| Title: | Hepatocyte spheroids as a viable in vitro model for recapitulation of complex in vivo metabolism pathways of loratadine in humans. |
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| Authors: | Chacko SA; Department of Metabolism and Pharmacokinetics, Bristol-Myers Squibb Research and Development, Princeton, NJ, USA., Ly VT; Department of Metabolism and Pharmacokinetics, Bristol-Myers Squibb Research and Development, Princeton, NJ, USA., Christopher LJ; Department of Metabolism and Pharmacokinetics, Bristol-Myers Squibb Research and Development, Princeton, NJ, USA., Gan J; Department of Metabolism and Pharmacokinetics, Bristol-Myers Squibb Research and Development, Princeton, NJ, USA. |
| Source: | Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2020 Jun; Vol. 50 (6), pp. 621-629. Date of Electronic Publication: 2019 Oct 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1366-5928 |
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| DOI: | 10.1080/00498254.2019.1675100 |
