A novel MCT1 and MCT4 dual inhibitor reduces mitochondrial metabolism and inhibits tumour growth of feline oral squamous cell carcinoma.

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Title: A novel MCT1 and MCT4 dual inhibitor reduces mitochondrial metabolism and inhibits tumour growth of feline oral squamous cell carcinoma.
Authors: Khammanivong A; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota., Saha J; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota., Spartz AK; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota., Sorenson BS; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota., Bush AG; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota., Korpela DM; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota., Gopalakrishnan R; Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, Minnesota.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Jonnalagadda S; Department of Chemistry and Biochemistry, University of Minnesota, Duluth, Minnesota., Mereddy VR; Department of Chemistry and Biochemistry, University of Minnesota, Duluth, Minnesota., O'Brien TD; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota.; Stem Cell Institute, University of Minnesota, Minneapolis, Minnesota., Drewes LR; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Department of Biomedical Sciences, University of Minnesota Medical School Duluth, Duluth, Minnesota., Dickerson EB; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.; Animal Cancer Care and Research Program, University of Minnesota, St. Paul, Minnesota.
Source: Veterinary and comparative oncology [Vet Comp Oncol] 2020 Sep; Vol. 18 (3), pp. 324-341. Date of Electronic Publication: 2019 Nov 19.
Publication Type: Journal Article
Journal Info: Publisher: Blackwell Country of Publication: England NLM ID: 101185242 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5829 (Electronic) Linking ISSN: 14765810 NLM ISO Abbreviation: Vet Comp Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1476-5829
DOI:10.1111/vco.12551