Inhibition of tyrosine kinase receptor signaling attenuates fibrogenesis in an ex vivo model of human renal fibrosis.

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Title: Inhibition of tyrosine kinase receptor signaling attenuates fibrogenesis in an ex vivo model of human renal fibrosis.
Authors: Bigaeva E; Department of Pharmaceutical Technology and Biopharmacy, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands., Stribos EGD; Department of Pharmaceutical Technology and Biopharmacy, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.; Division of Nephrology, Department of Internal Medicine, University Medical Center University of Groningen, Groningen, The Netherlands., Mutsaers HAM; Department of Pharmaceutical Technology and Biopharmacy, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Piersma B; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Leliveld AM; Department of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., de Jong IJ; Department of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Bank RA; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Seelen MA; Division of Nephrology, Department of Internal Medicine, University Medical Center University of Groningen, Groningen, The Netherlands., van Goor H; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Wollin L; Boehringer Ingelheim Pharma, Biberach, Germany., Olinga P; Department of Pharmaceutical Technology and Biopharmacy, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands., Boersema M; Department of Pharmaceutical Technology and Biopharmacy, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.
Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2020 Jan 01; Vol. 318 (1), pp. F117-F134. Date of Electronic Publication: 2019 Nov 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1522-1466
DOI:10.1152/ajprenal.00108.2019