View in EDS

Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2.

Saved in:
Bibliographic Details
Title: Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2.
Authors: Kidger AM; Signalling Laboratory, The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom. simon.cook@babraham.ac.uk andrew.kidger@babraham.ac.uk., Munck JM; Astex Pharmaceuticals, 436 Cambridge Science Park, Cambridge, United Kingdom., Saini HK; Astex Pharmaceuticals, 436 Cambridge Science Park, Cambridge, United Kingdom., Balmanno K; Signalling Laboratory, The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom., Minihane E; Signalling Laboratory, The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom., Courtin A; Astex Pharmaceuticals, 436 Cambridge Science Park, Cambridge, United Kingdom., Graham B; Astex Pharmaceuticals, 436 Cambridge Science Park, Cambridge, United Kingdom., O'Reilly M; Astex Pharmaceuticals, 436 Cambridge Science Park, Cambridge, United Kingdom., Odle R; Signalling Laboratory, The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom., Cook SJ; Signalling Laboratory, The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom. simon.cook@babraham.ac.uk andrew.kidger@babraham.ac.uk.
Source: Molecular cancer therapeutics [Mol Cancer Ther] 2020 Feb; Vol. 19 (2), pp. 525-539. Date of Electronic Publication: 2019 Nov 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1538-8514
DOI:10.1158/1535-7163.MCT-19-0505