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Identification of Selective Inhibitors of Plasmodium N-Myristoyltransferase by High-Throughput Screening.

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Bibliographic Details
Title: Identification of Selective Inhibitors of Plasmodium N-Myristoyltransferase by High-Throughput Screening.
Authors: Harupa A; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.; Novartis Institute for Biomedical Research , Emeryville , California 94608 , United States., De Las Heras L; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Colmenarejo G; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Lyons-Abbott S; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States., Reers A; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States., Caballero Hernandez I; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Chung CW; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Charter D; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Myler PJ; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States., Fernández-Menéndez RM; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Calderón F; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Palomo S; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Rodríguez B; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Berlanga M; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Herreros-Avilés E; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Staker BL; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States., Fernández Álvaro E; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Kaushansky A; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States.; Department of Global Health , University of Washington , Seattle , Washington 98195 , United States.
Source: Journal of medicinal chemistry [J Med Chem] 2020 Jan 23; Vol. 63 (2), pp. 591-600. Date of Electronic Publication: 2020 Jan 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-4804
DOI:10.1021/acs.jmedchem.9b01343