Identification of Selective Inhibitors of Plasmodium N-Myristoyltransferase by High-Throughput Screening.

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Title: Identification of Selective Inhibitors of Plasmodium N-Myristoyltransferase by High-Throughput Screening.
Authors: Harupa A; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.; Novartis Institute for Biomedical Research , Emeryville , California 94608 , United States., De Las Heras L; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Colmenarejo G; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Lyons-Abbott S; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States., Reers A; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States., Caballero Hernandez I; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Chung CW; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Charter D; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Myler PJ; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States., Fernández-Menéndez RM; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Calderón F; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Palomo S; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Rodríguez B; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Berlanga M; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Herreros-Avilés E; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Staker BL; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States., Fernández Álvaro E; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain., Kaushansky A; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States.; Department of Global Health , University of Washington , Seattle , Washington 98195 , United States.
Source: Journal of medicinal chemistry [J Med Chem] 2020 Jan 23; Vol. 63 (2), pp. 591-600. Date of Electronic Publication: 2020 Jan 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification of Selective Inhibitors of Plasmodium N-Myristoyltransferase by High-Throughput Screening.
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  Data: <searchLink fieldCode="AU" term="%22Harupa+A%22">Harupa A</searchLink>; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.; Novartis Institute for Biomedical Research , Emeryville , California 94608 , United States.<br /><searchLink fieldCode="AU" term="%22De+Las+Heras+L%22">De Las Heras L</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Colmenarejo+G%22">Colmenarejo G</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Lyons-Abbott+S%22">Lyons-Abbott S</searchLink>; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States.<br /><searchLink fieldCode="AU" term="%22Reers+A%22">Reers A</searchLink>; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States.<br /><searchLink fieldCode="AU" term="%22Caballero+Hernandez+I%22">Caballero Hernandez I</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Chung+CW%22">Chung CW</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Charter+D%22">Charter D</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Myler+PJ%22">Myler PJ</searchLink>; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States.<br /><searchLink fieldCode="AU" term="%22Fernández-Menéndez+RM%22">Fernández-Menéndez RM</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Calderón+F%22">Calderón F</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Palomo+S%22">Palomo S</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez+B%22">Rodríguez B</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Berlanga+M%22">Berlanga M</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Herreros-Avilés+E%22">Herreros-Avilés E</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Staker+BL%22">Staker BL</searchLink>; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Structural Genomics Center for Infectious Disease , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States.<br /><searchLink fieldCode="AU" term="%22Fernández+Álvaro+E%22">Fernández Álvaro E</searchLink>; GlaxoSmithKline , Tres Cantos, Madrid 28760 , Spain.<br /><searchLink fieldCode="AU" term="%22Kaushansky+A%22">Kaushansky A</searchLink>; Center for Infectious Disease Research , Seattle , Washington 98109 , United States.; Seattle Children's Research Institute , Seattle , Washington 98109 , United States.; Department of Global Health , University of Washington , Seattle , Washington 98195 , United States.
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2020 Jan 23; Vol. 63 (2), pp. 591-600. <i>Date of Electronic Publication: </i>2020 Jan 08.
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        Value: 10.1021/acs.jmedchem.9b01343
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