Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.
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| Title: | Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1. |
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| Authors: | Rudan Njavro J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Klotz J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Dislich B; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Institute of Pathology, University of Bern, Switzerland., Wanngren J; Division of Neurogeriatrics, Department of NVS, Center for Alzheimer Research, Karolinska Institutet, Stockholm, Sweden., Shmueli MD; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Department of Immunology, The Weizmann Institute of Science, Rehovot, Israel., Herber J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Kuhn PH; Institute of Pathology, Technical University of Munich, Munich, Germany., Kumar R; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Department of Neurology, Ludwig Maximilian University of Munich, Munich, Germany., Koeglsperger T; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Department of Neurology, Ludwig Maximilian University of Munich, Munich, Germany., Conrad M; Institute of Developmental Genetics, Helmholtz Zentrum München, Neuherberg, Germany., Wurst W; Institute of Developmental Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Genome Engineering, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Developmental Genetics, School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Feederle R; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; German Research Center for Environmental Health, Institute for Diabetes and Obesity, Monoclonal Antibody Core Facility, Helmholtz Zentrum München, Neuherberg, Germany.; Core Facility Monoclonal Antibodies, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Vlachos A; Department of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Germany.; Center for Basics in Neuromodulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, Germany., Michalakis S; Department of Ophthalmology, Ludwig Maximilian University of Munich, Munich, Germany., Jedlicka P; Faculty of Medicine, ICAR3R - Interdisciplinary Centre for 3Rs in Animal Research, Justus-Liebig-University, Giessen, Germany.; Neuroscience Center, Institute of Clinical Neuroanatomy, Goethe University, Frankfurt am Main, Germany.; Frankfurt Institute for Advanced Studies, Frankfurt am Main, Germany., Müller SA; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. |
| Source: | FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Feb; Vol. 34 (2), pp. 2465-2482. Date of Electronic Publication: 2019 Dec 27. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1530-6860 |
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| DOI: | 10.1096/fj.201902347R |
